Allergy and allergic diseases : the new mechanisms and therapeutics
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Bibliographic Information
Allergy and allergic diseases : the new mechanisms and therapeutics
Humana Press, c2010
- : pbk.
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Includes bibliographical references and index
Description and Table of Contents
Description
Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book's content is divided into both basic and clinical sections, with emphasis on various components of the immune and inflammatory response as they relate to the development of allergic disease. Topics span the range from molecular biology to clinical symptomatology, with an effort to make this of interest to as broad a constituency as possible. This book will therefore be of substantial interest to specialists in Clinical Immunology and Allergy, scientists studying the cellular and molecular biology of in flammation and immunity, as well as internists, teachers, developers of medical school curricula, and members of industry focused on drug discovery and therapeutics. Indeed, a separate section has been added to deal with some specific issues in this latter field.
Table of Contents
Part I. Epidemiology/IGE. Molecular Mechanisms of Isotype Switching to IGE, Donata Vercelli. Cytokines and IGE Regulation, Juha Punnonen and Jan E. de Vries. Environmental Allergens, Thomas A. E. Platts-Mills, Judith A. Woodfolk, and Lisa M. Wheatley. Ontogeny of Allergy, Bengt Bjorksten. Part II. Inflammation: Cellular Aspects. The Role of the Bone Marrow in Allergic Disease, Mark D. Inman, Roma Sehmi, Paul M. O'Byrne, and Judah A. Denburg. The Role of Mast Cells in Inflammation and Homeostasis, Angus J. MacDonald, Fiona L. Wills, Tong-Jun Lin, and A. Dean Befus. Human Langerhans Cells, Thomas Bieber. Eosinophils, Redwan Moqbel and Paige Lacy. Role of Basophils in Allergic Reactions, Peter Valent. Neurogenic Inflammation in Allergic Disease, Peter J. Barnes. Inflammation: Th1/Th2 Cells, Sergio Romagnani. T-Cells in the Pathogenesis of Asthma and Allergic Diseases, Marc Humbert and Stephen R. Durham. Role of CD8+ T-Cells in the Regulation of Immunoglobulin E, Paul A. MacAry and David M. Kemeny. Airway Wall Structure, Peter K. Jeffery, Mariusz J. Gizycki, and Andrew V. Rogers. Epithelium, Mary H. Perdue and Derek M. McKay. Part III. Inflammation: Molecular Aspects. Proinflammatory Cytokines in Allergic Disease, Daniel L. Hamilos. Hemopoietic Cytokines: Function, Receptor, and Signal Transduction, Hirokazu Kurata and Ken-ichi Arai. Adhesion Receptors in Allergic Disease, Andrew J. Wardlaw. Cell/Cytokine Interactions, David H. Broide. Signaling in Mast Cells, Anthony P. Sampson and Martin K. Church. Signaling in Human Basophils, Donald MacGlashan, Jr. Eosinophil Signal Transduction, Hirohita Kita. Part IV. Pathogenesis. Pathogenesis of Allergic Rhinitis, Niels Mygind and Ronald Dahl. Pathogenetic Mechanisms of Urticaria, Allen P. Kaplan. Atopic Eczema, Johannes Ring, Ulf Darsow, and Dietrich Abeck. Pathogenesis of Asthma, Paul M. O'Byrne. Pathogenesis of Allergic Conjunctivitis, Sergio Bonini and Stefano Bonini. Part V. Therapeutics. Glucocorticoids (Corticosteroids),Christopher J. Corrigan. ss-Agonists, Harold S. Nelson. Sodium Cromglycate and Nedocromil Sodium, Alan M. Edwards, Alexis E. Harper, Ken Rainey, and Alan A. Norris. Airway Remodeling and Repair, Peter M. Hockey, Ratko Djukanovic, William R. Roche, and Stephen T. Holgate. Index.
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