Biomedical nanotechnology : methods and protocols
著者
書誌事項
Biomedical nanotechnology : methods and protocols
（Methods in molecular biology / John M. Walker, series editor, 726）（Springer protocols）
Humana Press, c2011
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Due to their unique size-dependent properties, nanomaterials have the potential to revolutionize the detection, diagnosis, and treatment of disease by offering superior capabilities compared to conventionally-used materials. Biomedical Nanotechnology: Methods and Protocols brings together experts from a wide variety of fields to provide a practical overview of biomedical nanotechnology, from the conception of novel materials in the laboratory to the application of such structures in the clinic. After a brief introductory chapter, the first section consists of protocol chapters which provide hands-on information on the synthesis of a variety of solution-phase and surface-bound nanomaterials and their application in sensing, imaging, and/or therapeutics, while the second section consists of a series of case studies and review chapters that discuss the toxicology of nanomaterials, the regulatory pathways to US Food and Drug Administration (FDA) approval of these materials, their patenting, marketing, and commercialization, and the legal and ethical issues surrounding their use. Written in the highly successful Methods in Molecular Biology (TM) series format, many chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and insightful tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and authoritative, Biomedical Nanotechnology: Methods and Protocols surveys this exciting field from the most vital angles in order to provide a comprehensive reference for scientists and researchers of all different backgrounds looking to utilize the numerous versatile applications of nanomaterial technologies.
目次
1. Biomedical Nanotechnology
Sarah J. Hurst
Part I: Using Nanomaterials in Sensing, Imaging, and Therapeutics
2. Multiplexed Detection of Oligonucleotides with Biobarcoded Gold Nanoparticle Probes
Jae-Seung Lee
3. Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance
Jered B. Haun, Tae-Jong Yoon, Hakho Lee, and Ralph Weissleder
4. Real-Time Quantum Dot Tracking of Single Proteins
Jerry C. Chang and Sandra J. Rosenthal
5. Titanium Dioxide Nanoparticles in Advanced Imaging and Nanotherapeutics
Tijana Rajh, Nada M. Dimitrijevic, and Elena A. Rozhkova
6. Surface Modification and Biomolecule Immobilization on Polymer Spheres for Biosensing Applications
Chris R. Taitt, Lisa C. Shriver-Lake, George P. Anderson, and Frances S. Ligler
7. Multivalent Conjugation of Peptides, Proteins, and DNA to Semiconductor Quantum Dots
Duane E. Prasuhn, Kimihiro Susumu, and Igor L. Medintz
8. A Single SnO2 Nanowire-Based Microelectrode
Jun Zhou, Yaguang Wei, Qin Kuang, and Zhong Lin Wang
9. Biosensing Using Nanoelectromechanical Systems (NEMS)
Ashish Yeri and Di Gao
10. Nano "Fly Paper" Technology for the Capture of Circulating Tumor Cells
Shutao Wang, Gwen E. Owens, and Hsian-Rong Tseng
11. Polymeric Nanoparticles for Photodynamic Therapy
Yong-Eun Koo Lee and Raoul Kopelman
12. Hydrogel Templates for the Fabrication of Homogeneous Polymer Microparticles
Ghanashyam Acharya, Matthew McDermott, Soo Jung Shin, Haesun Park, and Kinam Park
13. Antibacterial Application of Engineered Bacteriophage Nanomedicines: Antibody-Targeted, Chloramphenicol Prodrug Loaded Bacteriophages for Inhibiting the Growth of Staphylococcus aureus Bacteria
Lilach Vaks and Itai Benhar
14. Viruses as Nanomaterials for Drug Delivery
Dustin Lockney, Stefan Franzen, and Steven Lommel
15. Applications of Carbon Nanotubes in Biomedical Studies
Hongwei Liao, Bhavna Paratala, Balaji Sitharaman, and Yuhuang Wang
16. Electrospun Nanofibrous Scaffolds for Engineering Soft Connective Tissues
Roshan James, Udaya S. Toti, Cato T. Laurencin, and Sangamesh G. Kumbar
17. Peptide Amphiphiles and Porous Biodegradable Scaffolds for Tissue Regeneration in the Brain and Spinal Cord
Rutledge G. Ellis-Behnke and Gerald E. Schneider
18. Computational Simulations of the Interaction of Lipid Membranes with DNA-Functionalized Gold Nanoparticles
One-Sun Lee and George C. Schatz
Part II: Translating Nanoscience and Technology from the Lab to the Clinic
19. Cytotoxic Assessment of Carbon Nanotube Interaction with Cell Cultures
Hanene Ali-Boucetta, Khuloud T. Al-Jamal, and Kostas Kostarelos
20. Nanoparticle Toxicology: Measurements of Pulmonary Hazard Effects Following Exposures to Nanoparticles
Christie M. Sayes, Kenneth L. Reed, and David B. Warheit
21. Nanoparticle Therapeutics: FDA Approval, Clinical Trials, Regulatory Pathways, and Case Study
Aaron C. Eifler and C. Shad Thaxton
22. Legislating the Laboratory?: Promotion and Precaution in a Nanomaterials Company
Robin Phelps and Erik Fisher
23. Navigating the Patent Landscapes for Nanotechnology: English Gardens or Tangled Grounds?
Douglas J. Sylvester and Diana M. Bowman
24. Scientific Entrepreneurship in the Materials and Life Science Industries
Jose Amado Dinglasan, Darren J. Anderson, and Keith Thomas
25. Applying the Marketing Mix (5 P's) to Bionanotechnology
Michael S. Tomczyk
26. Managing the "Known Unknowns": Theranostic Cancer Nanomedicine and Informed Consent
Fabrice Jotterand and Archie A. Alexander
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