Neuronal guidance : the biology of brain wiring : a subject collection from Cold Spring Harbor perspectives in biology
Author(s)
Bibliographic Information
Neuronal guidance : the biology of brain wiring : a subject collection from Cold Spring Harbor perspectives in biology
Cold Spring Harbor Laboratory Press, c2011
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Note
Includes bibliographical references and index
Contents of Works
- Mechanisms and molecules of neuronal wiring : a primer / Alex L. Kolodkin and Marc Tessier-Lavigne
- Cellular strategies of axonal pathfinding / Jonathan Raper and Carol Mason
- Navigating intermediate targets : the nervous system midline / Barry J. Dickson and Yimin Zou
- Motor axon pathfinding / Dario Bonanomi and Samuel L. Pfaff
- Molecular and cellular mechanisms of lamina-specific axon targeting / Andrew D. Huberman, Thomas R. Clandinin, and Herwig Baier
- Self-avoidance and tiling : mechanisms of dendrite and axon spacing / Wesley B. Grueber and Alvaro Sagasti
- Visual map development : bidirectional signaling, bifunctional guidance molecules, and competition / David A. Feldheim and Dennis D.M. O'Leary
- Topographic mapping : the olfactory system / Takeshi Imai, Hitoshi Sakano, and Leslie B. Vosshall
- Wiring the brain : the biology of neuronal guidance / Alain Chedotal and Linda J. Richards
- Human genetic disorders of axon guidance / Elizabeth C. Engle
- Initiating and growing an axon / Franck Polleux and William Snider
- The growth cone cytoskeleton in axon outgrowth and guidance / Erik W. Dent, Stephanie L. Gupton, and Frank B. Gertler
- Rho and ras gtpases in axon growth, guidance, and branching / Alan Hall and Giovanna Lalli
- Signaling from axon guidance receptors / Greg J. Bashaw and Rüdiger Klein
- Trafficking guidance receptors / Bettina Winckler and Ira Mellman
- Guiding neuronal cell migrations / Oscar Maron ... [et al.]
- Guidance molecules in synapse formation and plasticity / Kang Shen and Christopher W. Cowan
- Guidance molecules in axon pruning and cell death / Pierre Vanderhaeghen and Hwai-Jong Cheng
- Guidance molecules in axon regeneration / Roman J. Giger, Edmund R. Hollis II, and Mark H. Tuszynski
- Axon guidance molecules in vascular patterning / Ralf H. Adams and Anne Eichmann
Description and Table of Contents
Description
During the development of the brain growing nerves send out neuronal processes (axons and dendrites) that connect them to other nerve cells, sensory organs, and muscle tissue. Correct targeting of these is the basis for wiring of the entire nervous system and depends on attractive and repulsive molecular cues that guide the developing neurons to the appropriate destination. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the mechanisms underlying neuronal guidance and branching and their roles in the development and function of the nervous system. The contributors examine the major guidance cues and their receptors, the intracellular signaling pathways they activate, and their function in the context of important phenomena such as laminar organization and dendrite spacing. Other chapters consider the roles of guidance cues in development of neuronal circuits dedicated to the processing of particular sensory stimuli, such as the visual and olfactory systems. In addition, they cover the roles played by guidance cues and their receptors in neuronal regeneration and human genetic disorders, revealing important clinical implications of work in this field. The book also contains chapters discussing the function of guidance molecules in other processes, such as neuronal cell body migration, axon pruning, and regulation of neuronal cell death. In addition, it explores their roles outside the nervous system for example, in development of the vasculature. This volume is thus of general interest to cell and developmental biologists, as well as all neurobiologists interested in how the nervous system develops and functions.
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