Nutrition, epigenetic mechanisms, and human disease
著者
書誌事項
Nutrition, epigenetic mechanisms, and human disease
CRC Press, c2011
- : hardcover
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
As nutrition research is shifting its focus from epidemiology and physiology to effects of nutrients at the molecular level, a uniquely tailored diet that corresponds to the demands of our genetic signature is emerging as an indispensable need. Using high-throughput genomic tools, nutrigenomics unravels the influence of micro- and macronutrients as potent dietary signals regulating metabolic pathways and unmasks how susceptible genotypes are predisposed to diet-related diseases.
Selected topics from this field have been covered in some books, but no other comprehensive text on epigenetics, nutrition, and human health and disease is available, until now. This book illustrates nutrition's influence on epigenetic inheritance and the mechanisms underlying the modification of the metabolic imprint of an individual. This enriched understanding of nutrigenomics can be applied to master a tailored diet that can alleviate imprinted metabolic syndromes. Specifically, the book focuses on:
Maternal, perinatal, and neonatal nutrition
Epigenetic mechanisms and cancer
Impacts of dietary factors, folate deficiency and DNA methylation
Nutrition's influence on genetic imprinting
The basics of nutrigenomics and epigenetic regulation
目次
Preface, Acknowledgments, The Editors, Contributors, Chapter 1 Nutritional Epigenetics and Disease Prevention: Are We There Yet?1, Chapter 2 Aging by Epigenetics: Nutrition, An Epigenetic Key to Long Life., Chapter 3 Folate and DNA Methylation, Chapter 4 Dietary Components, Epigenetics, and Cancer, Chapter 5 Dietary Factors, Histone Modifications, and Cancer Prevention, Chapter 6 Nutrition, Epigenetics, and Vascular Function, Chapter 7 Role of Epigenetic Machinery and MicRNAs in Diet-Induced Hepatocarcinogenesis, Chapter 8 Epigenetic Mechanisms in Lung Inflammation and Chronic Airway Diseases and Intervention by Dietary Polyphenols, Chapter 9 Glycemic Memory and Epigenetic Changes, Chapter 10 Maternal Nutrition, Intrauterine Development, and Disease Risks in the Offspring through Epigenetic Regulation of Gene Expression, Chapter 11 Nutritional Epigenetics: Impact on Metabolic Syndrome, Chapter 12 Nutrition and the Emerging Epigenetic Paradigm: Lessons from Neurobehavioral Disorders, Chapter 13 Interactions between Folate, Other B Vitamins, DNA Methylation, and Neurodevelopmental Disorders, Chapter 14 Dietary Factors and the Emerging Role of Epigenetics in Neurodegenerative Diseases
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