Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology

著者

    • Han, Chao
    • Davis, Charles B. (Charles Baldwin)
    • Wang, Binghe, PhD

書誌事項

Evaluation of drug candidates for preclinical development : pharmacokinetics, metabolism, pharmaceutics, and toxicology

edited by Chao Han, Charles B. Davis, Binghe Wang

(Wiley series in drug discovery and development / Binghe Wang, series editor)

J. Wiley, c2010

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注記

"A John Wiley and Sons, Ltd., publication"

Includes bibliographical references and index

収録内容

  • Pharmacokinetics in preclinical drug development : an overview / Dion R. Brocks
  • The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You
  • Cytochrome P450 : structure, function and application in drug discovery and development
  • The role of drung metabolism and metabolite identification in drug discovery / Xiangming Guan
  • Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani
  • Prediction of the pharmacokinetics in humans / Chao Han, Ramesh Bambal
  • Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki
  • Safety assessment in drug discovery / Vito G. Sasseville, Willian R. Foster, and Bruce D. Car
  • Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown

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