Enzyme inhibition in drug discovery and development : the good and the bad

著者

書誌事項

Enzyme inhibition in drug discovery and development : the good and the bad

edited by Chuang Lu, Albert P. Li

Wiley, c2010

  • : cloth

大学図書館所蔵 件 / 全4件

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注記

"A John Wiley & Sons, Inc., publication"

Includes bibliographical references and index

収録内容

  • The drug discovery process / Gerald T. Miwa
  • Medicinal chemistry of the optimization of enzyme inhibitors / Geraldine Harriman, Amy Elder, and Indranath Ghosh
  • Bioanalytical technologies in drug discovery / Jing-Tao Wu
  • Safety biomarkers in drug development : emerging trends and implications / Eric R. Fedyk
  • The role of drug metabolism in drug discovery / Tonika Bohnert and Liang-Shang Gan
  • Applied pharmacokinetics in drug discovery and development / Hua Yang ... [et al.]
  • Enzyme inhibition and inactivation : cytochrome P450 enzymes / R. Scott Obach
  • Cytochrome P450 induction / Edward L. LeCluyse ... [et al.]
  • Inhibition of drug-metabolizing enzymes in the gastrointestinal tract and its influence on the drug-drug interaction prediction / Aleksandra Galetin and J. Brian Houston
  • Enzyme inhibition in various in vitro systems / Ping Zhao
  • Cytochrome P450 Degradation and its clinical relevance / Mingxiang Liao ... [et al.]
  • Complexities of working with UDP-Giucuronosyltransferases (UGTs) : focus on enzyme inhibition / Michael B. Fisher
  • Evaluation of inhibitors of drug metabolism in human hepatocytes / Albert P. Li and Chuang Lu
  • Grapefruit juice and its constituents as new esterase inhibitors / Suresh K. Balani
  • Transporter-Xenobiotic Interactions : an important aspect of drug development studies / Gang Luo, Richard Ridgewell, and Thomas Guenthner
  • Polymorphisms of drug transporters and their clinical implications / Cindy Q. Xia and Johnny J. Yang
  • Clinical drug interactions due to metabolic inhibition : prediction, assessment, and interpretation / Lisa L. von Moltke and David J. Greenblatt
  • Predicting interindividual variability of metabolic drug-drug interactions : identifying the causes and accounting for them using a systems approach / Amin Rostami-Hodjegan
  • NF-KB : mechanism, tumor biology, and inhibitors / Lenny Dang
  • G-Protein-Coupled receptors as drug targets / Wenyan Miao and Lijun Wu
  • Pharmacological modulation of ion channels for the treatment of chronic pain / Yi Liu and Ning Qin
  • Targeting the mTOR pathway for tumor therapeutics / Wei Chen
  • HIV-1 protease inhibitors as antiretroviral agents / Selgei V. Gulnik, Elena Afonina, and Michael Eissenstat

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