Epigenetic regulation of lymphocyte development
著者
書誌事項
Epigenetic regulation of lymphocyte development
（Current topics in microbiology and immunology, v. 356）
Springer, c2012
- hbk.
- ebk.
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
目次
Preface.- Roles of lineage-determining transcription factors in establishing open chromatin - lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility: Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.- Subject Index
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