Multiple myeloma
著者
書誌事項
Multiple myeloma
（Remedica state of the art series）
Remedica, c2011
2nd ed
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Multiple myeloma is the second most common hematologic malignancy, affecting over 14,000 patients per year in the USA. Over the last ten years, there has been a dramatic increase in our understanding of the biology of multiple myeloma, which has provided insights into mechanisms of cytotoxic resistance, both as inherent characteristics of the myeloma cell and the protective interaction between the tumor and its bone marrow microenvironment. Through this greater understanding, a large array of new therapies has been engendered and a significant impact is being made on patient outcome as a result. This second edition of "Multiple Myeloma" has been revised and updated to provide a concise overview of the state of the art in this field.
目次
Epidemiology, etiology, and molecular pathogenesis - Approaches to initial management and supportive care - Mechanisms of drug resistance and therapeutic implications - Novel biologic therapies - Thalidomide and lenalidomide treatment - High-dose chemotherapy and bone marrow transplantation - Bone disease - Gene expression profiling and cytogenetics - Sequencing of treatment and the future of "tailored" approaches to therapy - Immunotherapy
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