Optogenetics : tools for controlling and monitoring neuronal activity

著者

書誌事項

Optogenetics : tools for controlling and monitoring neuronal activity

edited by Thomas Knöpfel, Edward S. Boyden

（Progress in brain research, 196）

Elsevier, 2012

1st ed

  • : hardcover

大学図書館所蔵 件 / 全12件

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注記

Includes bibliographical references and index

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内容説明・目次

内容説明

Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology. These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to development to cardiology. The book contains a dozen chapters written by world experts on these topics, half focusing on the optogenetic molecular tools themselves, and half on the genetic and hardware approaches that make them powerfully useful in intact tissues and organisms.

目次

A comprehensive concept of optogenetics Guillaume P. Dugue, Walther Akemann, and Thomas Knoepfel Optogenetic excitation of neurons with channelrhodopsins: light instrumentation, expression systems, and channelrhodopsin variants John Y. Lin Genetically encoded molecular tools for light-driven silencing of targeted neurons Brian Y. Chow, Xue Han, and Edward S. Boyden Genetically encoded probes for optical imaging of brain electrical activity Amelie Perron, Walther Akemann, Hiroki Mutoh and Thomas Knoepfel Neural activity imaging with genetically encoded calcium indicators Lin Tian, Jasper Akerboom, Eric R. Schreiter, and Loren L. Looger Manipulating cellular processes using optical control of protein-protein interactions Chandra L. Tucker Two-photon optogenetics Dan Oron, Eirini Papagiakoumou, F. Anselmi, and Valentina Emiliani Zebrafish as an appealing model for optogenetic studies Joshua Simmich, Eric Staykov, and Ethan Scott Genetic targeting of specific neuronal cell types in the cerebral cortex Alan Urban, and Jean Rossier Mouse transgenic approaches in optogenetics Hongkui Zeng, and Linda Madisen Optogenetics in the nonhuman primate Xue Han Optogenetic Reporters: Fluorescent Protein-Based Genetically-Encoded Indicators of Signaling and Metabolism in the Brain Mathew Tantama, Yin Pun Hung,and Gary Yellen

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