Basic clinical pharmacokinetics
著者
書誌事項
Basic clinical pharmacokinetics
Wolters Kluwer/Lippincott Williams & Wilkins Health, c2010
5th ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help pharmacy students in clinical settings and busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among students, clinical professors, and practitioners.
Part I provides a basic review of pharmacokinetic principles, with extensive explanations, graphic illustrations, and detailed algorithms. Part II explains the clinical applications of these principles to problems commonly encountered in the practice setting with specific drugs. This edition includes the latest information on the clinical use of serum drug concentrations. New case studies and examples demonstrate the application of pharmacokinetics in today's clinical practice.
目次
Part I: BASIC PRINCIPLES
Bioavailability
Administrative Rate
Desired Plasma Concentration
Volume of Distribution
Clearance
Elimination Rate Constant(K) and Half-Life (t1/2)
Maximum and Minimum Plasma Concentrations
Selecting the Appropriate Equation
Interpretation of Plasma Drug Concentrations
Creatinine Clearance
Dialysis of Drugs
Part II: DRUG MONOGRAPHS
1. Aminoglycoside Antibiotics
2. Carbamazepine
3. Digoxin
4. Ethosuximide
5. Immunosuppressants: Cyclosporine, Tacrolimus and Sirolimus
6. Lidocaine
7. Lithium
8. Methotrexate (MTX)
9. Phenobarbital
10. Phenytoin
11. Theophylline
12. Valproic Acid
13. Vancomycin
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