Genomic diversity of Bacillus-related species
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書誌事項
Genomic diversity of Bacillus-related species
（Nova biomedical）
Nova Science Publishers, c2008
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注記
Includes bibliographical references (p. [81]-92) and index
内容説明・目次
内容説明
A great number of aerobic endospore-forming Gram-positive Bacillus species have been isolated on a number of occasions from a variety of terrestrial and deep-sea environments, including the Mariana Trench which has a depth of 10,897 m. Some of these Bacullus species are known to have various capabilities for adapting to extreme environments. In fact, Bacillus-related species can grow in a wide range of environments -- at pH 2-12, at temperatures between 5 and 78 DegreesC, in salinity from 0 to 30% NaCl, and under pressures from 0.1 Mpa to at least 30 Mpa. The author is now exploring how these adaptive capabilities, as reflected in their genomes, were acquired and what intrinsic genomic structures are present in Bacillus-related species that have allowed them to adapt to such a wide range of environments. To answer these questions, the author initiated a genome sequencing project in early 1998 and have to present determined the entire genomic sequences of three extremophilic bacilli: alkaliphilic Bacillus halodurans, extremely halotolerant and alkaliphilic Oceanobacillus iheyensis, and thermophilic Geobacillus kaustophilus. The author provides the first comparative analysis of the extremophilic bacillar genomes with those of three other phylogenetically related mesophilic and neutrophilic bacilli, B. subtilis, B. anthracis and B. cereus, in order to highlight the commonality and diversity of the bacillar genome.
目次
- Preface
- Introduction
- Phylogenetic Classification of Bacilli
- Estimation of the Genome Size of Extremophilic Bacillus-Related Species
- Alkaliphilic Bacillus Halodurans
- Extremely Halotolerant and Alkaliphilic Oceanobacillus Iheyensis
- Thermophilic Geobacillus Kaustophilus
- Determination of Genome Sequences of Extremophilic Bacilli
- Whole Genome Shotgun Sequencing of Three Extremophilic Bacilli
- Gene Finding and Annotation
- Genomic Features of Extremophilic Bacilli
- Alkaliphilic B Halodurans
- General Features
- Other Genomic Features
- Extremely Halotolerant and Alkaliphilic O Iheyensis
- General Features
- Thermophilic G Kaustophilus
- General Features
- Construction of the ExtremoBase Genome Database
- Transposable Elements in Extremophilic Bacillar Genomes
- IS Elements and Group II Intron in the B. Halodurans Genome
- IS Elements with IRs that Generate TSD
- IS Elements with IRs that Do not Generate TSD
- IS Elements Lacking IRs
- Group II Intron
- Species-Wide Distribution of IS Elements and Group II Introns Derived from B Halodurans C-125
- Characterisation of Newly Identified Transposon and IS Element in B Halodurans A59
- Bacilli-Wide Distribution of IS Elements and Group II Introns Derived from B Halodurans C-125
- IS Elements, Transposon, and Group II Introns in the O Iheyensis Genome
- IS Elements and Group II Intron in the G. Kaustophilus Genome
- Behaviour of IS Elements in the Extremophilic Bacillar Genomes
- Bacteriophage
- Comparative Analysis of Transposable Elements Disseminated among Bacilli
- IS Elements
- Group II Introns
- Orthologous Analysis of the Genome of Bacillus-Related Species
- Genomic Features Related to Extremophilic Phenotypes
- Alkaliphic Phenotype
- Candidate Genes Involved in Alkaliphily
- Extreme Halotolerant Phenotype
- Candidate Genes Involved in the Extreme Halotolerance
- Thermophilic Phenotype
- Candidate Genes Involved in Thermophily
- Other Thermophilic Properties
- Conclusion
- Index.
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