Bisphosphonates and osteonecrosis of the jaw
著者
書誌事項
Bisphosphonates and osteonecrosis of the jaw
（Annals of the New York Academy of Sciences, v.1218）
Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2011
- :pbk.
注記
"This volume presents manuscripts stemming from the conference entitled 'Bisphosphonates & Osteonecrosis of the Jaw,' held May 19, 2007 at the New York Academy of Sciences."
Includes bibliographical references
収録内容
- Bisphosphonates and osteonecrosis of the jaw : proceedings of an international conference / John P. Bilezikian and J. T. Gribic
- The use of bisphosphonates in cancer treatment / Robert Coleman
- Use of bisphosphonates in the management of postmenopausal osteoporosis / Socrates E. Papapoulos
- Bisphosphonate use in conditions other than osteoporosis / Stuart L. Silverman
- Bisphosphonate-related osteonecrosis of the jaw : an overview / Salvatore L. Ruggiero
- Epidemiology and risk factors for osteonecrosis of the jaw in cancer patients / Ana O. Hoff ... [et al.]
- The impact of bisphosphonates on oral health : lessons from the past and opportunities for the future / Athanasios I. Zavras
- Potential pathophysiological mechanisms in osteonecrosis of the jaw / Regina Landesberg ... [et al.]
- Biochemical markers of bone turnover in osteonecrosis of the jaw in patients with osteoporosis and advanced cancer involving the bone / Serge Cremers and Azeez Farooki
内容説明・目次
内容説明
In the last several years, reports of patients treated with bisphosphonates (primarily those delivered intravenously) have emerged associating their use with osteonecrosis of the jaw (ONJ). More than a thousand cases of bisphosphonate-associated ONJ have been identified since the first cases were reported in 2001. In these, ONJ rarely occurs "spontaneously"; the vast majority have been associated as a consequence to oral surgical procedures. Although most of the reports of ONJ have occurred in patients following the use of high dose IV therapy for metastatic bone disease, there are also reports of ONJ in patients taking oral bisphosphonates. Since millions of patients take oral bisphosphonates for the treatment of osteoporosis, it is timely to review what is known and needs to be learned about this emerging issue in patient care-to develop a consensus on the definition of ONJ, as well as to explore potential risk factors and pathogenic mechanisms of ONJ and to explore strategies to move research forward. This volumes seeks to improve awareness of the condition and the need for increased screening and improved diagnosis of ONJ. It also explores possible treatment options for ONJ to help guide future areas for research.
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