CiNii Books - Sande's HIV/AIDS medicine, Medical management of AIDS 2012

Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS epidemic and the different needs of Western vs. developing-world patients and clinicians. Diagnose AIDS manifestations confidently by comparing them to clinical images. Improve patient outcomes with the latest findings on the management of AIDS as a chronic illness. Efficiently review essential data through numerous at-a-glance tables. Get the most relevant information available on pediatric HIV and AIDS issues; anti-retroviral drugs, including integrase inhibitors; and the use of second- and third-line anti-retroviral drugs in resource-poor settings. Stay current on the latest actionable information, such as using antiretroviral therapy in patients with tuberculosis and drug-resistant tuberculosis; antiretroviral therapy; immune reconstitution inflammatory syndromes (IRIS); and implementation of the HPV vaccine.

Table of Contents

Contents Preface vii Contributors ix Acknowledgments xv SECTION 1: Epidemiology and biology of HIV infection 1 The global epidemiology of HIV/AIDS 3 Irum Zaidi, Kevin M De Cock 2 The origins and diversification of HIV 15 Michael Worobey, Guan-Zhu Han 3 Molecular biology of HIV: implications for new therapies 25 Warner C Greene, B Matija Peterlin, Matthew H Stremlau 4 The immune response to HIV 45 Clive M Gray, Pamela Gumbi, Lycias Zembe, Mopo Radebe, Bruce Walker 5 Viral and host determinants of HIV-1 disease progression 59 Danielle van Manen, Angelique B van 't Wout, Hanneke Schuitemaker 6 Acute HIV infection 77 Anthony D Kelleher, David A Cooper 7 Biology of HIV-1 transmission 89 Julie Overbaugh SECTION 2: Prevention, diagnosis, and treatment of HIV infection 8 The design of a global HIV vaccine 97 Jerome H Kim, Nelson L Michael 9 HIV prevention 113 Salim S Abdool Karim 10 Laboratory testing for HIV infection 123 James C Shepherd, Oliver Laeyendecker, Thomas C Quinn 11 Overview of antiretroviral therapy 133 Susa Coffey, Paul A Volberding 12 Development and transmission of HIV drug resistance 155 Mark A Wainberg, Gerasimos J Zaharatos 13 Pharmacology of antiretroviral drugs 169 Concepta Merry, Charles W Flexner 14 Complications resulting from antiretroviral therapy for HIV infection 177 David Nolan, Simon Mallal, Peter Reiss SECTION 3: Diseases associated with HIV infection 15 Oral complications of HIV infection 195 John S Greenspan, Deborah Greenspan 16 Ocular manifestations of AIDS 207 James P Dunn 17 Global HIV and dermatology 219 Toby Maurer, Robert Michelleti 18 Gastrointestinal disorders in HIV including diarrhea 237 Marie-Louise C Vachon, Douglas T Dieterich 19 Primary neurological manifestation of HIV/AIDS 249 David B Clifford, Mengesha A Teshome 20 Psychiatric barriers and the international AIDS epidemic 257 Chiadi U Onyike, Andrew F Angelino, Glenn J Treisman 21 Cardiovascular complications of HIV infection 267 Rakesh K Mishra 22 Endocrine complications of HIV infection 275 Steven A Taylor, Carl Grunfeld, Morris Schambelan 23 Renal complications of HIV infection 287 Jula K Inrig, Lynda A Szczech, Trevor E Gerntholtz, Paul E Klotman 24 Pneumocystis pneumonia 297 Robert J Blount, J Lucian Davis, Laurence Huang 25 Other HIV-related pneumonias 313 John G Bartlett 26 HIV-associated tuberculosis 325 Leyla Azis, Edward C Jones-Lopez, Jerrold J Ellner 27 Disseminated Mycobacterium avium complex and other atypical mycobacterial infections 349 Mark A Jacobson 28 Candida in HIV infection 359 William G Powderly 29 Cryptococcosis and other fungal infections (histoplasmosis and coccidioidomycosis) in HIV-infected patients 369 Kathleen R Page, Richard E Chaisson, Merle Sande 30 Infection due to Penicillium marneffei 389 Thira Sirisanthana, Khuanchai Supparatpinyo 31 AIDS-associated toxoplasmosis 397 Pablo A Moncada, Jose G Montoya 32 Hepatitis virus infections 411 Marion G Peters, Monika Sarkar 33 Bartonella infections in HIV-infected individuals 421 Jane E Koehler 34 Management of herpesvirus infections (cytomegalovirus, herpes simplex virus, and varicella-zoster virus) 433 W Lawrence Drew, Kim S Erlich 35 HIV-associated malignancies 455 Ronald T Mitsuyasu 36 STDs and syphilis 467 Elysia Larson, Jeffrey D Klausner SECTION 4: Prevention and management 37 Prevention of mother-to-child transmission of HIV-1 485 Lynne M Mofenson 38 Managing HIV infection in children and adolescents 509 Elizabeth H Doby, Andrew T Pavia 39 Special issues regarding women with HIV infection 521 Ruth M Greenblatt, Monica Gandhi 40 HIV disease among substance users: treatment issues 537 R Douglas Bruce, Frederick L Altice, Gerald Friedland 41 The HIV-infected international traveler 551 Malcolm John Index 561

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Sande's HIV/AIDS medicine, Medical management of AIDS 2012

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