Protein dimerization and oligomerization in biology

Bibliographic Information

Protein dimerization and oligomerization in biology

edited by Jacqueline M. Matthews

(Advances in experimental medicine and biology, v. 747)

Springer Science+Business Media , Landes Bioscience, c2012

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Includes bibliographical references and index

Description and Table of Contents

Description

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Table of Contents

Dimers, Oligomers, Everywhere.- The Detection and Quantitation of Protein Oligomerization.- Computational and Structural Characterisation of Protein Associations.- Death by Caspase Dimerization.- The Relationship between Oligomeric State and Protein Function.- Oligonucleotide Binding Proteins: The Occurrence of Dimer and Multimer Formation.- Homo- and Heterodimerization in Transcriptional Regulation.- OligomeriZation at the Membrane: Potassium Channel Structure and Function.- Implications of 3D Domain Swapping for Protein Folding, Misfolding and Function.- From artificial antibodies to nanosprings: The biophysical properties of repeat proteins.

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