Dubois' lupus erythematosus and related syndromes

著者

書誌事項

Dubois' lupus erythematosus and related syndromes

edited by Daniel J. Wallace, Bevra Hannahs Hahn ; associate editors, David Isenberg ... [et al.]

Elsevier/Saunders, c2013

8th ed

タイトル別名

Lupus erythematosus and related syndromes

大学図書館所蔵 件 / 全23件

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注記

Rev. ed. of: Dubois' lupus erythematosus / editors, Daniel J. Wallace, Bevra Hannahs Hahn. 7th ed. c2007

Includes bibliographical references and index

内容説明・目次

内容説明

Recognized for more than 45 years as the definitive text in the field, Dubois' Lupus Erythematosus and Related Syndromes strikes the perfect balance between basic science and clinical expertise, providing the evidence-based findings, treatment consensuses, and practical clinical information you need to confidently diagnose and manage SLE. Broaden your understanding with comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. Experience clinical scenarios with vivid clarity through a heavily illustrated, full-color format which includes fundamental images of lupus rashes as well as graphs, algorithms, and differential diagnosis comparisons. Discover the latest in systemic lupus erythematosus with new chapters on important emerging topics such as socioeconomic and disability aspects; and rigorously updated chapters that include expanded coverage of the nervous system, and the most in-depth discussion of immunity and regulatory cells. Learn from the very best. World-renowned rheumatologists Drs. Daniel Wallace and Bevra Hannahs Hahn, along with new associate editors Drs. Michael Weisman, Ronald Van Vollenhoven, Nan Shen, and David Isenberg, present definitive coverage on new and rapidly changing areas in the field. Rely on it anytime, anywhere! Access the full text, image bank, and bonus online-only chapters at www.expertconsult.com. Dubois' Lupus Erythematosus was first published in 1966. For the past forty years, the product has distinguished itself internationally as the go-to reference on lupus and related diseases. For rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on systemic lupus erythematosus (SLE) and related disorders, this product delivers a complete arsenal of information on SLE, connective tissue diseases, and the antiphospholipid syndromes.

目次

Section I: What is Lupus? 1. Definition and classification of Lupus and Lupus-Related Disorders 2. The Epidemiology of Lupus Section II: The Pathogenesis of Lupus 3. The Pathogenesis of SLE 4. Genetics of Human SLE 5. Epigenetics of Lupus 6. The Innate Immune System in SLE 7. Cytokines and Interferons in Lupus 8. The Structure and Derivation of Antibodies and Autoantibodies 9. T Cells 10. Regulatory Cells in SLE 11. Apoptosis, Necrosis, and Autophagy 12. Abnormalities in Immune Complex Clearance and Fc? Receptor Function 13. Neural-Immune Interactions: Principles and Relevance to SLE 14. Complement and SLE 15. Mechanisms of Acute Inflammation and Vascular Injury in SLE 16. Mechanisms of Tissue Damage - Free Radicals and Fibrosis 17. Animal Models of SLE 18. Pathogenic Mechanisms in Lupus Nephritis Section III: Autoantibodies 19. Immune Tolerance Defects in Lupus 20. Autoantibodies 21. Autoantigenesis and Entigen-Based Therapy and Vaccination in SLE Section IV: Clinical Aspects of SLE 22. Overview and Clinical Presentation 23. Pathomechanisms of Cutaneous Lupus Erythematosus 24. Skin Disease in Cutaneous Lupus Erythematosus 25. The Musculoskeletal System and Bone Metabolism 26. Pathogenesis and Treatment of Atherosclerosis in Lupus 27. Cardiopulmonary Disease in SLE 28. Pathogenesis of the Nervous System 29. Clinical Aspects of the Nervous System 30. Psychopathology, Neurodiagnostic Testing, and Imaging 31. Ocular, Aural, and Oral Manifestations 32. Management of Sj gren Syndrome in Patients with SLE 33. Gastrointestinal and Hepatic Manifestations 34. Hematologic and Lymphoid Abnormalities in SLE 35. Clinical and Epidemiologic Features of Lupus Nephritis Section V: The Reproductive System & Hormones 36. Pregnancy in Women with SLE 37. Neonatal Lupus Erythematosus 38. Reproductive and Hormonal Issues in Women with Autoimmune Diseases Section VI: Special Considerations, Subsets of SLE and Lupus-Related Syndromes 39. Drug-Induced Lupus: Etiology, Pathogenesis, and Clinical Aspects 40. SLE in Childhood and Adolescence 41. Mixed Connective Tissue Disease and Undifferentiated Connective Tissue Disease 42. Clinical Aspects of the Antiphospholipid Syndrome Section VII: Assessment of Lupus 43. Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in SLE 44. Differential Diagnosis and Disease Associations 45. SLE and Infections 46. Clinical Measures, Metrics and Indices Section VIII: Management of SLE 47. Principles of Therapy, Local Measures, Nonsteroidal Medications 48. Systemic Glucocorticoid Therapy in SLE 49. Antimalarial Medications 50. Immunosuppressive Drug Therapy 51. Specialized Treatment Approaches and Niche Therapies for Lupus Subsets 52. Adjunctive and Preventive Measures 53. Novel Therapies for SLE: Biological Agents Available in Practice Today 54. Critical Issues in Drug Development for SLE 55. Socioeconomic and Disability Aspects Section IX: Outcomes and Future Considerations 56. Investigational Agents and Future Therapy for SLE 57. Mortality in SLE Appendix: Lupus Resource Materials Index

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