書誌事項

Uremic toxins

edited by Toshimitsu Niwa

(Wiley-Interscience series on mass spectrometry)

John Wiley & Sons, c2012

大学図書館所蔵 件 / 4

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注記

Includes bibliographical references and index

収録内容

  • Uremic toxins : an integrated overview of definition and classification / Richard J. Glassock and Shaul G. Massry
  • Classification and a list of uremic toxins / Nathalie Neirynck ... [et al.]
  • Analysis of uremic toxins with mass spectrometry? / Toshimitsu Niwa
  • Indoxyl sulfate / Toshimitsu Niwa
  • P-cresyl sulfate / Anneleen Pletinck, Raymond Vanholder, and Griet Glorieux
  • 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid / Toshimitsu Niwa
  • Phenylacetic acid / Anna Schulz and Joachim Jankowski
  • Homocysteine and hydrogen sulfide : two opposing aspects in the pathobiology of sulfur compounds in chronic renal failure / Alessandra F. Perna and Diego Ingrosso
  • Guanidino compounds / Sunny Eloot ... [et al.]
  • Asymmetric dimethylarginine / Vladimir Teplan and Jaroslav Racek
  • Nicotinamide metabolites / Przemyslaw Rutkowski and Boleslaw Rutkowski
  • Dicarbonyls (glyoxal, methylglyoxal, and 3-deoxyglucosone) / Naila Rabbani and Paul J. Thornalley
  • Glucose degradation products in peritoneal dialysis / Monika Pischetsrieder and Sabrina Gensberger
  • Dinucleoside polyphosphates / Joachim Jankowski and Vera Jankowski
  • Parathyroid hormone / Shaul G. Massry and Miroslaw Smogorzewski
  • β2-microglobulin / Suguru Yamamoto ... [et al.]
  • Cytokines / Bjorn Anderstam, Bengt Lindholm, and Peter Stenvinkel
  • Free immunoglobulin light chains / Gerald Cohen and Walter H. Hirl
  • Advanced glycation end-products (AGEs) / Naila Rabbani and Paul J. Thornalley
  • Oxidized albumin / Maurizio Bruschi ... [et al.]
  • Therapeutic removal of uremic toxins by hemodialysis / Tammy L. Sirich, Pavel Aronov, and Timothy W. Meyer
  • Therapeutic removal of uremic toxins by peritoneal dialysis / Malgorzata Debowska ... [et al.]
  • Therapeutic removal of uremic toxins by oral sorbent / Toshimitsu Niwa

内容説明・目次

内容説明

Reviews all the latest basic and clinical research findings With contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices. Uremic Toxins is divided into three sections: Section One, Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxins Section Two, Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, ss2-microglobulin, and AGEs Section Three, Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbent All chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field. Reviewing all the latest basic and clinical research findings, Uremic Toxins will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.

目次

PREFACE ix CONTRIBUTORS xi SECTION 1: UREMIC TOXINS 1 1. Uremic Toxins: An Integrated Overview of Definition and Classification 3 Richard J. Glassock and Shaul G. Massry 2. Classification and a List of Uremic Toxins 13 Nathalie Neirynck, Rita De Smet, Eva Schepers, Raymond Vanholder, and Griet Glorieux 3. Analysis of Uremic Toxins with Mass Spectrometry 35 Toshimitsu Niwa SECTION 2: SELECTED UREMIC TOXINS 51 4. Indoxyl Sulfate 53 Toshimitsu Niwa 5. p-Cresyl Sulfate 77 Anneleen Pletinck, Raymond Vanholder, and Griet Glorieux 6. 3-Carboxy-4-methyl-5-propyl-2-furanpropionic Acid 87 Toshimitsu Niwa 7. Phenylacetic Acid 99 Anna Schulz and Joachim Jankowski 8. Homocysteine and Hydrogen Sulfide, Two Opposing Aspects in the Pathobiology of Sulfur Compounds in Chronic Renal Failure 109 Alessandra F. Perna and Diego Ingrosso 9. Guanidino Compounds 125 Sunny Eloot, Griet Glorieux, Peter Paul De Deyn, and Raymond Vanholder 10. Asymmetric Dimethylarginine 143 Vladimyr Teplan and Jaroslav Racek 11. Nicotinamide Metabolites 163 Boleslaw Rutkowski and Przemyslaw Rutkowski 12. Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone) 177 Naila Rabbani and Paul J. Thornalley 13. Glucose Degradation Products in Peritoneal Dialysis 193 Monika Pischetsrieder and Sabrina Gensberger 14. Dinucleoside Polyphosphates 209 Joachim Jankowski and Vera Jankowski 15. Parathyroid Hormone 227 Shaul G. Massry and Miroslaw Smogorzewski 16. b2-Microglobulin 249 Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita, and Fumitake Gejyo 17. Cytokines 259 BjEUROorn Anderstam, Bengt Lindholm, and Peter Stenvinkel 18. Free Immunoglobulin Light Chains 279 Gerald Cohen and Walter H. HEUROorl 19. Advanced Glycation Endproducts (AGEs) 293 Naila Rabbani and Paul J. Thornalley 20. Oxidized Albumin 305 Maurizio Bruschi, Giovanni Candiano, Laura Santucci, and Gian Marco Ghiggeri SECTION 3: THERAPEUTIC REMOVAL OF UREMIC TOXINS 315 21. Therapeutic Removal of Uremic Toxins by Hemodialysis 317 Tammy L. Sirich, Pavel Aronov, and Timothy W. Meyer 22. Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis 331 Malgorzata Debowska, Elvia Garcya-Lopez, Jacek Waniewski, and Bengt Lindholm 23. Therapeutic Removal of Uremic Toxins by Oral Sorbent 359 Toshimitsu Niwa INDEX 373

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