Agrochemicals

著者

書誌事項

Agrochemicals

edited by Clemens Lamberth and Jürgen Dinges

(Bioactive heterocyclic compound classes)

Wiley-VCH, c2012

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注記

Formerly CIP Uk

Includes bibliographical references and index

内容説明・目次

内容説明

The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures. Often, these compounds show beneficial properties and are therefore applied as pharmaceuticals to treat diseases or as insecticides, herbicides or fungicides in crop protection. This volume presents important agrochemicals. Each of the 21 chapters covers in a concise manner one class of heterocycles, clearly structured as follows: * Structural formulas of most important examples (market products) *Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the agrochemical chemistry.

目次

IINTRODUCTION THE SIGNIFICANCE OF HETEROCYCLES FOR PHARMACEUTICALS AND AGROCHEMICALS Introduction Heterocycles as Framework of Biologically Active Compounds Fine-Tuning the Physicochemical Properties with Heterocycles Heterocycles as Prodrugs Heterocycles as Peptidomimetics Heterocycles as Isosteric Replacement of Functional Groups Heterocycles as Isosteric Replacement of Alicyclic Rings Heterocycles as Isosteric Replacement of other Heterocyclic Rings PART I: Herbicides TRIAZINE HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationships PYRIMIDINYL AND TRIAZINYLSULFONYLUREA HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship ACETOHYDROXYACID SYNTHASE INHIBITING TRIAZOLOPYRIMIDINE HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship HPPD-INHIBITING BENZOYLPYRAZOLE HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PYRIDYLOXYPHENOXYPROPIONATE HERBICIDES: INHIBITORS OF ACETYL-COA CARBOXYLASE Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationships IMIDAZOLINONE HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PROTOPORPHYRINOGEN-IX-OXIDASE-INHIBITING URACIL HERBICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship Part II: Fungicides BENZIMIDAZOLE FUNGICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship MORPHOLINE FUNGICIDES FOR THE TREATMENT OF POWDERY MILDEW Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship STEROL BIOSYNTHESIS INHIBITING TRIAZOLE FUNGICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship METHIONINE BIOSYNTHESIS-INHIBITING ANILINOPYRIMIDINE FUNGICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PHENYLPYRROLE FUNGICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship BROAD-SPECTRUM FUNGICIDALLY ACTIVE PYRIMIDINYLDIOXY STROBILURINS INHIBITING THE RESPIRATORY CHAIN Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PYRAZOLE CARBOXAMIDE FUNGICIDES INHIBITING SUCCINATE DEHYDROGENASE Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationships Part III: Insecticides AVERMECTIN INSECTICIDES AND ACARICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PYRIDINE AND THIAZOLE-CONTAINING INSECTICIDES AS POTENT AGONISTS ON INSECT NICOTINIC ACETYLCHOLINE RECEPTORS Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PYRAZOLE AND PYRIMIDINE ACARICIDES AND INSECTICIDES ACTING AS INHIBITORS OF MITOCHONDRIAL ELECTRON TRANSPORT AT COMPLEX I Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PHENYLPYRAZOLE-CONTAINING FIPROLE INSECTICIDES Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship PYRAZOLYLPYRIDINE ACTIVATORS OF THE INSECT RYANODINE RECEPTOR Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationships TETRONIC ACID INSECTICIDES AND ACARICIDES INHIBITING ACETYL-COA CARBOXYLASE Introduction History Synthesis Mode of Action Biological Activity Structure?Activity Relationship

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