Biosimulation : simulation of living systems

書誌事項

Biosimulation : simulation of living systems

Daniel A. Beard

(Cambridge texts in biomedical engineering)

Cambridge University Press, 2012

  • : hardback

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注記

Includes bibliographical references (p. [299]-303) and index

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内容説明・目次

内容説明

This practical guide to biosimulation provides the hands-on experience needed to devise, design and analyze simulations of biophysical processes for applications in biological and biomedical sciences. Through real-world case studies and worked examples, students will develop and apply basic operations through to advanced concepts, covering a wide range of biophysical topics including chemical kinetics and thermodynamics, transport phenomena, and cellular electrophysiology. Each chapter is built around case studies in a given application area, with simulations of real biological systems developed to analyze and interpret data. Open-ended project-based exercises are provided at the end of each chapter, and with all data and computer codes available online (www.cambridge.org/biosim) students can quickly and easily run, manipulate, explore and expand on the examples inside. This hands-on guide is ideal for use on senior undergraduate/graduate courses and also as a self-study guide for anyone who needs to develop computational models of biological systems.

目次

  • 1. Introduction to simulation of biological systems
  • 2. Transport and reaction of solutes in biological systems
  • 3. Physiologically-based pharmacokinetic modeling
  • 4. Cardiovascular systems simulation
  • 5. Chemical reaction systems: thermodynamics
  • 6. Chemical reaction systems: kinetics
  • 7. Chemical reaction systems: large-scale systems simulation
  • 8. Cellular electrophysiology
  • 9. Appendices: mathematical and computational techniques.

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