Emerging Raman applications and techniques in biomedical and pharmaceutical fields
著者
書誌事項
Emerging Raman applications and techniques in biomedical and pharmaceutical fields
(Biological and medical physics, biomedical engineering)
Springer, c2010
大学図書館所蔵 全1件
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注記
Includes bibliographical references and index
On title page: "With 62 figures"
内容説明・目次
内容説明
In recent years, Raman spectroscopy has undergone a major transformation from a specialist laboratory technique to a practical analytical tool. This change was driven on several parallel fronts by dramatic advances in laser instrumentation, detectors, spectrometers, and optical ?lter technology. This resulted in the advent of a new generation of compact and robust Raman instruments with improved sensitivity and ?exibility. These devices could be operated for the ?rst time by non-specialists outside the laboratory envir- ment. Indeed, Raman spectroscopy is now found in the chemical and phar- ceutical industries for process control and has very recently been introduced into hospitals. Handheld instruments are used in forensic and other security applications and battery-operated versions for ?eld use are found in envir- mental and geological studies. Simultaneously, major advances have been seen in the development of powerful processing methods, some driven by the progress of related spect- scopic methods such as NIR absorption spectroscopy. Numerous chemometric packages are available for advanced analysis of data.
These do not require specialist user knowledge (although caution is required in interpreting - sults) and provide further enhanced sensitivity and capability to the Raman technique. In this book we focus on two such major ?elds, biomedical and ph- maceutical. The book is aimed at life sciences and pharmaceutical re- erships. Accordingly, the chapter authors emphasize explanatory material with practical implications rather than focusing on mathematical detail.
目次
Lasers, Spectrographs, and Detectors.- Fiber-Optic Raman Probes for Biomedical and Pharmaceutical Applications.- Characterisation of Deep Layers of Tissue and Powders: Spatially Offset Raman and Transmission Raman Spectroscopy.- Applications of Raman and Surface-Enhanced Raman Scattering to the Analysis of Eukaryotic Samples.- Raman Imaging and Raman Mapping.- Coherent Raman Scattering Microscopy.- Raman Optical Activity of Biological Molecules.- Chemometric Methods for Biomedical Raman Spectroscopy and Imaging.- Discovery and Formulation.- Raman Spectroscopy: A Strategic Tool in the Process Analytical Technology Toolbox.- Emerging Dental Applications of Raman Spectroscopy.- Raman Spectroscopy of Ocular Tissue.- Raman Spectroscopy for Early Cancer Detection, Diagnosis and Elucidation of Disease-Specific Biochemical Changes.- Raman Spectroscopy of Bone and Cartilage.- Raman Microscopy and Imaging: Applications to Skin Pharmacology and Wound Healing.- Raman Spectroscopy of Blood and Urine Specimens.- Quantitative Raman Spectroscopy of Biomaterials for Arthroplastic Applications.- Raman Spectroscopy: A Tool for Tissue Engineering.- Applications of Raman Spectroscopy to Virology and Microbial Analysis.
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