Designing receptors for the next generation of biosensors

著者

    • Piletsky, Sergey A.
    • Whitcombe, Michael J.
    • Andreu, M. R. (M. Rosario)

書誌事項

Designing receptors for the next generation of biosensors

volume editors: Sergey A. Piletsky, Michael J. Whitcombe ; with contributions by M.R. Andreu ... [et al.]

(Springer series on chemical sensors and biosensors : methods and applications / Otto S. Wolfbeis series editor, 12)

Springer, c2013

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the detection of pathogenic microorganisms, the development of molecularly imprinted polymer (MIP) nanoparticles, the in silico design of MIPs and MIP-based sensors, and two chapters examining the development of sensors from an industrial point of view. The particular focus of all chapters is on practical aspects, either in the development process or the applications of the synthesized materials. This book will serve as an important reference work for business leaders and technology experts in the sensors and diagnostics sector.

目次

Multichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes Ana M. Costero, Margarita Parra, Salvador Gil, M. Rosario Andreu Learning from Proteins and Drugs: Receptors that Mimic Biomedically Important Binding Motifs Fraser Hof, Thomas Pinter Molecular Recognition of Nucleotides Hannes Y. Kuchelmeister, Carsten Schmuck Molecular Recognition of Oligopeptides and Protein Surfaces Hannes Y. Kuchelmeister, Carsten Schmuck Antimicrobial Peptides for Detection and Diagnostic Assays Lisa C. Shriver-Lake, Stella H. North, Scott N. Dean, Chris R. Taitt Plastic Antibodies Alessandro Poma, Michael Whitcombe, Sergey Piletsky Computational Approaches in the Design of Synthetic Receptors Sreenath Subrahmanyam, Kal Karim, and Sergey A. Piletsky MIP Sensors on the Way to Real-World Applications Ghulam Mustafa, Peter A. Lieberzeit Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications Ran Tel-Vered, Itamar Willner Design and Development of in vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management Christina Thomas, Rachel Weller Roska, Robert E. Carlson Evolving Trends in Transition Metal-Modified Receptor Design and Function Paul A. Bertin

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