Boron and gadolinium neutron capture therapy for cancer treatment
Author(s)
Bibliographic Information
Boron and gadolinium neutron capture therapy for cancer treatment
World Scientific, c2012
Available at / 4 libraries
-
No Libraries matched.
- Remove all filters.
Note
Includes bibliographical references (p. 215-240) and index
Description and Table of Contents
Description
The book focuses on two concurrent experimental therapies in cancer treatment known as boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT) using a variety of boron- and gadolinium-based compounds. Some of the gadolinium compounds serve the dual purpose as being MRI contrast agents and GdNCT agents. The book describes why BNCT & GdNCT were not at the forefront of the clinical trials during the past seven to eight decades since the discovery of neutrons by John Chadwick in 1932 and how the latest development in the synthesis of target boron- and gadolinium-based drugs has turned the area into the hottest one worthy of further investigation with the new clinical trials in the USA and elsewhere.
Table of Contents
- Introduction
- Principles of Neutron Capture Therapy
- Major NCT Drug Prototypes
- Boron Compounds-Based BNCT Agents
- Neutron Sources for NCT
- NCT Dosimetry and Treatment Planning
- Selected in vitro and in vivo Studies
- Clinical Trials
- Summary
- The Future of NCT
- Appendix: Clinical State of BNCT by US Department of Energy (DOE) as of 1997
- Acknowledgments
- References.
by "Nielsen BookData"
