A structural perspective on respiratory complex I : structure and function of NADH:ubiquinone oxidoreductase
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Bibliographic Information
A structural perspective on respiratory complex I : structure and function of NADH:ubiquinone oxidoreductase
Springer, c2012
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Includes bibliographical references and index
Description and Table of Contents
Description
The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.
Table of Contents
- Foreword
- Leonid Sazanov Part I: Structure and mechanism of complex I 1. Structure of complex I
- Rouslan Efremov and Leonid Sazanov 2. On the mechanism of the respiratory complex I
- Thorsten Friedrich, Petra Hellwig, and Oliver Einsle 3. Iron-sulfur clusters in complex I
- Eiko Nakamaru-Ogiso 4. Current Topics of the Inhibitors of Mitochondrial Complex I
- Hideto Miyoshi 5. My Fifty Years Association with Complex I Study
- Tomoko Ohnishi Part II: Evolution of complex I 6. The Evolutionary Relationship between Complex I and [NiFe]-hydrogenase
- Anne Volbeda and Juan C. Fontecilla-Camps 7. Recruitment of the antiporter module - a key event in complex I evolution
- Vamsi Krishna Moparthi and Cecilia Hagerhall Part III: Mutations in complex I subunits and medical implications 8. Characterization of Bacterial Complex I (NDH-1) by a Genetic Engineering Approach
- Takao Yagi, Jesus Torres-Bacete, Prem Kumar Sinha, Norma Castro-Guerrero, and Akemi Matsuno-Yagi 9. Cellular consequences of mtDNA-encoded mutations in NADH:ubiquinone oxidoreductase
- Mina Pellegrini, Jan A.M. Smeitink, Peter H.G.M. Willems and Werner J.H. Koopman Part IV: Subunit composition and assembly of mitochondrial complex I 10. The assembly of human complex I
- Jessica Nouws, Maria Antonietta Calvaruso, Leo Nijtmans 11. Complexes I in the green lineage
- Claire Remacle, Patrice Hamel, Veronique Larosa, Nitya Subrahmanian, Pierre Cardol Part V: Supercomplexes in mitochondria 12. Supramolecular organization of the respiratory chain
- Janet Vonck Index
by "Nielsen BookData"
