Molecular imaging in the clinical neurosciences

著者

書誌事項

Molecular imaging in the clinical neurosciences

edited by Gerhard Gründer

（Neuromethods, 71）（Springer protocols）

Humana Press, c2012

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function. In Molecular Imaging in the Clinical Neurosciences, experts in the field provide the reader with up-to-date information on the basic principles of molecular imaging and its major applications in the clinical neurosciences. Beginning with a section offering a comprehensive review of the methodological foundations from physics, chemistry, and mathematics including mathematical modeling, essential for meaningful data analysis, this detailed volume then continues with sections on the major biological principles and neurochemical targets relevant in current neuroimaging research and the major clinical applications from the fields of psychiatry and neurology. Written for the popular Neuromethods series, this work contains the kind of key description and implementation advice that guarantees successful results. Authoritative and cutting-edge, Molecular Imaging in the Clinical Neurosciences serves as a helpful source of knowledge for both basic and clinical scientists from psychology, psychiatry, neurology, nuclear medicine, nuclear chemistry, and the associated disciplines, all of which makes molecular imaging such a rewarding, interdisciplinary field of work.

目次

1. Instrumentation and Physical Principles Christoph Weirich and Hans Herzog 2. Molecular Neuroscience and the Quantification of Brain Dynamics Albert Gjedde and Dean F. Wong 3. Radiopharmaceutical Chemistry Markus Piel and Frank Roesch 4. Introduction to the Basics of Magnetic Resonance Imaging Klaus Moellenhoff, Ana-Maria Oros-Peusquens, and N. Jon Shah 5. Quantification of Cerebral Blood Flow Adriaan A. Lammertsma 6. The Assay of Enzyme Activity by Positron Emission Tomography Paul Cumming and Neil Vasdev 7. Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane Paul Cumming and Neil Vasdev 8. Quantification of Neuroreceptors and Neurotransporters Hiroshi Ito, Mika Naganawa, Chie Seki, Harumasa Takano, Iwao Kanno, and Tetsuya Suhara 9. Measuring Dopamine Synaptic Transmission with Molecular Imaging and Pharmacological Challenges: The State of the Art Marc Laruelle 10. Small Animal Imaging with Positron Emission Tomography (PET) Hideo Tsukada 11. Emission Imaging in Dementia Julie C. Price, Brian J. Lopresti, and Victor L. Villemagne 12. Neurochemical Imaging of Addictive Disorders Allegra Broft and Diana Martinez 13. Molecular Imaging of Mood Disorders Jeffrey H. Meyer 14. Molecular Imaging in Schizophrenia Oliver Howes 15. Imaging the Pathophysiology of Ischemic Cerebrovascular Disease Wolf-Dieter Heiss 16. Molecular Imaging of Brain Tumors Karl-Josef Langen 17. Molecular Imaging in Parkinson's Disease Laura K. Teune and Karl L. Leenders 18. Epilepsy Alexander Hammers Christoph Weirich and Hans Herzog

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