Handbook of drug screening
著者
書誌事項
Handbook of drug screening
(Drugs and the pharmaceutical sciences, v. 196)
Informa Healthcare, c2009
2nd ed
- : hardcover
大学図書館所蔵 全1件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.
With extensively updated content and 21 new chapters, this text examines:
quality and efficiency of drug target validation and potential drug compound selection
reducing assay costs and improvement in assay technology
data quality improvement
trends in drug discovery
how drug screening can minimize adverse drug effects
recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry
目次
Trends in Drug Discovery. Screening Strategies and Infrastructure in Drug Discovery. Logistics in Progression of Compounds to Clinical Development. Assay Technologies in Drug Screening. Proteomics Technologies in Drug Discovery. GPCR Screens. Nuclear Hormone Receptor Screens. Emerging Novel HTS Technologies for Cell Based Assays. In vitro Strategies for Ion Channel Screening in Drug Discovery. Wheat from Chaff: General and Mechanistic Triage of Screening Hits for Enzyme Targets. Protein Kinases and Phosphatases. MicroRNA Strategies in Drug Discovery. Strategies for Screening Biological in Drug Discovery. Cryopreserved Cells in Functional Cell-Based HTS Assays. High Content Screening Assay development. ADME-TOX, PK and Drug Metabolism in Drug Discovery. Compound Management for Drug Screening. Practical Approach to Quantitative High-Throughput Screening. Enabling the Large Scale Analysis of Quantitative High Throughput Screening Data. Nanotechnology in Drug Discovery.
「Nielsen BookData」 より