Oligomerization and allosteric modulation in G-protein coupled receptors

著者

• Kenakin, Terrence P.

書誌事項

Oligomerization and allosteric modulation in G-protein coupled receptors

edited by Terry Kenakin

（Progress in molecular biology and translational science, v. 115）

Elsevier/Academic Press, c2013

• hbk.

内容説明・目次

内容説明

In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology. Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research.

目次

Approaches for Probing Allosteric Interactions at 7 Transmembrane Spanning Receptors Michael T. Klein, Paige N. Vinson and Colleen M. Niswender Pharmacology of Metabotropic Glutamate Receptor Allosteric Modulators: Structural Basis and Therapeutic Potential for CNS Disorders Karen J. Gregory, Meredith J. Noetzel and Colleen M. Niswender Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor Drug Discovery Magalie Rochville, Julio Martin, Jeffrey Clifford Jerman & Evi Kostenis G Protein-Coupled Receptors in Cancer : Biochemical Interactions and Drug Design Yves Audigier, Francois-Xavier Picault, Carline Chaves-Almagro and Bernard Masri GPCRs in Stem Cell Function Van A. Doze and Dianne M. Perez Application of Receptor Theory to Allosteric Modulation of Receptors David A. Hall What Ligand-Gated Ion Channels Can Tell Us about the Allosteric Regulation of G protein-Coupled Receptors Frederick J. Ehlert Modelling Cooperativity Effects in Dimeric G Protein-Coupled Receptors Jesus Giraldo Chemokine Receptor Oligomerization and Allostery Bryan Stephens and Tracy M. Handel Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators Peishen Zhao, Wendy Cladman, Hubert HM Van Tol and Peter Chidiac

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詳細情報

• NII書誌ID(NCID): BB12036968
• ISBN:
  • 9780123945877
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam
• ページ数/冊数: xiii, 471p.,[8] p. of plates
• 大きさ: 24 cm
• 分類:
  • DC23 : 572.696
• 件名:
  • LCSH : G proteins -- Receptors
  • LCSH : Allosteric regulation
  • LCSH : Allosteric proteins
• 親書誌ID:
  • BA88526923