G protein coupled receptors : structure
Author(s)
Bibliographic Information
G protein coupled receptors : structure
(Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 520)
Elsevier/Academic Press, c2013
- : hardback
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Note
Includes bibliographical references and indexes
Description and Table of Contents
Description
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain.
Table of Contents
G Protein Coupled Receptors: Techniques for Probing Structure
Comformational Ensemble View of G Protein-Coupled Receptors and The Effect of Mutations and Ligand Binding
Structural Evolution of G-Protein-Coupled Receptors: A Sequence Space Approach
Directed Evolution of G Protein-Coupled Receptors for High Functional Expression and Detergent Stability
The Role of Hydrophobic Amino Acids in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors
Structure of ss-Adrenergic Receptors
Advances in Methods to Characterize Ligand-Induced Ionic Lock and Rotamer Toggle Molecular Switch in G-Protein Coupled Receptors
Crystallogenesis of Adenosine A2A Receptor - T4 Lysozyme Fusion Protein: A Practical Route for the Structure
Probing GPCR Structure: Adenosine and P2Y Nucleotide Receptors
Strategies for Studying the Ligand Binding Site of GPCRs: Photoaffinity Labeling of the VPAC1 Receptor, a Prototype of Class B GPCRs
Expression of Mammalian G Protein-Coupled Receptors in Caenorhabditis Elegans
Expression, Purification and Structural Analysis of Intracellular C-Termini from Metabotropic Glutamate Receptors
Unnatural Amino Acid Mutagenesis of GPCRs Using Amber Codon Suppression and Bioorthogonal Labeling
Mapping a Ligand Binding Site Using Genetically-Encoded Photoactivatable Crosslinkers
Alternative mRNA Splicing of G Protein-Coulped Receptors
Functional Residues of the CB1 Cannabinoid Receptor
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