G protein coupled receptors : structure

著者

• Conn, P. Michael

書誌事項

G protein coupled receptors : structure

edited by P. Michael Conn

（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 520）

Elsevier/Academic Press, c2013

• : hardback

注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR oligomerization in the brain.

目次

G Protein Coupled Receptors: Techniques for Probing Structure Comformational Ensemble View of G Protein-Coupled Receptors and The Effect of Mutations and Ligand Binding Structural Evolution of G-Protein-Coupled Receptors: A Sequence Space Approach Directed Evolution of G Protein-Coupled Receptors for High Functional Expression and Detergent Stability The Role of Hydrophobic Amino Acids in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors Structure of ss-Adrenergic Receptors Advances in Methods to Characterize Ligand-Induced Ionic Lock and Rotamer Toggle Molecular Switch in G-Protein Coupled Receptors Crystallogenesis of Adenosine A2A Receptor - T4 Lysozyme Fusion Protein: A Practical Route for the Structure Probing GPCR Structure: Adenosine and P2Y Nucleotide Receptors Strategies for Studying the Ligand Binding Site of GPCRs: Photoaffinity Labeling of the VPAC1 Receptor, a Prototype of Class B GPCRs Expression of Mammalian G Protein-Coupled Receptors in Caenorhabditis Elegans Expression, Purification and Structural Analysis of Intracellular C-Termini from Metabotropic Glutamate Receptors Unnatural Amino Acid Mutagenesis of GPCRs Using Amber Codon Suppression and Bioorthogonal Labeling Mapping a Ligand Binding Site Using Genetically-Encoded Photoactivatable Crosslinkers Alternative mRNA Splicing of G Protein-Coulped Receptors Functional Residues of the CB1 Cannabinoid Receptor

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詳細情報

• NII書誌ID(NCID): BB12040546
• ISBN:
  • 9780123918611
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam ; Tokyo
• ページ数/冊数: liv, 384 p., [12] p. of plates
• 大きさ: 24 cm
• 分類:
  • DC23 : 572.696
• 件名:
  • LCSH : G proteins -- Receptors
• 親書誌ID:
  • BA00197543