Host-pathogen interactions in streptococcal diseases
Author(s)
Bibliographic Information
Host-pathogen interactions in streptococcal diseases
（Current topics in microbiology and immunology, 368）
Springer, c2013
- : hbk
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.
Table of Contents
Group A Streptococcal Diseases and Their Global Burden
Anna P. Ralph and Jonathan R Carapetis
Molecular Markers for the Study of Streptococcal Epidemiology
David J McMillan, Martina L Sanderson-Smith, Pierre Smeesters and Kadaba S Sriprakash
Epidemiology and Pathogenicity of Zoonotic Streptococci
Marcus Fulde and Peter Valentin-Weigand
Adherence and Invasion of Streptococci to Eukaryotic Cells and Their Role
in Disease Pathogenesis
Manfred Rohde and G. Singh Chhatwal
Common Regulators of Virulence in Streptococci
Nadja Patenge, Tomas Fiedler and Bernd Kreikemeyer
Host-Pathogen Interactions in Streptococcal Immune Sequelae
D. Patric Nitsche-Schmitz and Gursharan S. Chhatwal
Immunopathogenesis of Streptococcal Deep Tissue Infections
Linda Johansson and Anna Norrby-Teglund
Modulation of the Coagulation System During Severe Streptococcal Disease
Oonagh Shannon, Heiko Herwald and Sonja Oehmcke
Group A Streptococcal Vaccine Candidates: Potential for the Development of a Human Vaccine
Anna Henningham, Christine M. Gillen and Mark J. Walker
Clinical Management of the Most Common Group A -Hemolytic Streptococcal Infections
Edward Kaplan
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