Advanced topics in forensic DNA typing : methodology

Bibliographic Information

Advanced topics in forensic DNA typing : methodology

by John Butler

Academic/Elsevier, 2011, c2012

  • : hbk

Available at  / 2 libraries

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Note

"Contribution of the National Institue of Standards and Technology, 2011"--T.p. verso

Formerly CIP Uk

Includes bibliographical references and index

Contents of Works

  • Sample collection, storage, and characterization
  • DNA extraction methods
  • DNA quantitation
  • PCR amplification: capabilities and cautions
  • Short tandem repeat (STR) loci and kits
  • Capillary electrophoresis: principles and instrumentation
  • Quality assurance and validation
  • DNA databases: uses and issues
  • Missing persons and disaster victim identification efforts
  • Degraded DNA
  • Low-level DNA testing: issues, concerns, and solutions
  • Single nucleotide polymorphisms and applications
  • Y-chromosome DNA testing
  • Mitochondrial DNA analysis
  • X-chromosome analysis
  • Non-human DNA
  • New technologies and automation
  • Legal aspects of DNA testing and the scientific expert in court

Description and Table of Contents

Description

Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.

Table of Contents

1. Sample Collection, Storage, and Characterization2. DNA Extraction Methods3. DNA Quantitation 4. PCR Amplification: Capabilities and Cautions5. Short Tandem Repeat (STR) Loci and Kits6. Capillary Electrophoresis: Principles and Instrumentation7. Quality Assurance and Validation8. DNA Databases: Uses and Issues9. Missing Persons and Disaster Victim Identification Efforts10. Degraded DNA11. Low-Level DNA Testing: Issues, Concerns, and Solutions12. Single Nucleotide Polymorphisms and Applications13. Y-Chromosome DNA Testing14. Mitochondrial DNA Analysis15. X-Chromosome Analysis16. Non-Human DNA17. New Technologies and Automation18. Legal Aspects of DNA Testing and the Scientific Expert in CourtAppendix 1 Reported Sizes and Sequences of STR AllelesAppendix 2 Familial DNA Searches: Potential, Pitfalls, and Privacy ConcernsAppendix 3 List of Suppliers for DNA Instruments, Reagents, ServicesAppendix 4 Interviews Supporting Legal Aspects of DNA Testing

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