Structural aspects of protein synthesis
著者
書誌事項
Structural aspects of protein synthesis
（Series in structural biology, v. 1）
World Scientific, c2013
2nd ed. / Anders Liljas, Måns Ehrenberg
- : hardcover
- :pbk
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注記
Includes bibliographical references (p. 347-429) and index
内容説明・目次
内容説明
This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and cryo-EM forms part of an interactive framework that involves biochemistry and molecular computation. The book provides a comprehensive overview of translation in light of the structural results. It is a valuable resource for scientists in this and related fields, as well as for students taking courses with a focus on translation.There is no other book in this field currently except the previous edition of this book. The authors have for a long time worked in the field of structure and function of the translation system.
目次
- The Basics of Translation
- Historical Milestones
- Methods of Studying Structure
- The Message - mRNA
- The Adaptor - tRNA
- The Workbench - Ribosomes
- The Structure of the Ribosome
- Ribosomal Sites and Ribosomal States
- The Catalysts - Translation Factors
- Inhibitors of Protein Synthesis - Antibiotics, Resistance
- The Process - Translation
- Protein Processing, Folding and Targeting
- Evolution of the Translation Apparatus.
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