Inhibitors of the Ras superfamily G-proteins

著者

• Tamanoi, Fuyuhiko
• Der, Channing J.

書誌事項

Inhibitors of the Ras superfamily G-proteins

edited by Fuyuhiko Tamanoi

（The enzymes / edited by Paul D. Boyer, Edwin G. Krebs, v. 33-34）

Elsevier/Academic Press, 2013

• pt. A
• pt. B

注記

pt. A : edited by Fuyuhiko Tamanoi

pt. B : edited by Fuyuhiko Tamanoi, Channing J. Der

内容説明・目次

巻冊次

pt. A ISBN 9780124167490

内容説明

This special volume of The Enzymes is targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses inhibitors of the Ras superfamily G-proteins.

目次

The Ras superfamily G-proteins Fuyuhiko Tamanoi NMR Study to Identify a Ligand-Binding Pocket in Ras Till Maurer and Weiru Wang The Allosteric Switch and Conformational States in Ras GTPase Affected by Small Molecules Christian W. Johnson and Carla Mattos State 1(T) Inhibitors of Activated Ras Hans Robert Kalbitzer and Michael Spoerner Sugar-Based Inhibitors of Ras Activation: Biological Activity and Identification of Ras-Inhibitor Binding Interface Alessandro Di Domizio and Francesco Peri Development of EHop-016, a Small Molecule Inhibitor of Rac Suranganie Dharmawardhane Aptamer-Derived Peptide Inhibitors of Rho Guanine Nucleotide Exchange Factors Susanne Schmidt and Anne Debant Targeting the Dbl and Dock-Family RhoGEFs: a Yeast-Based Assay to Identify Cell-Active Inhibitors of Rho-Controlled Pathways Anne Blangy and Philippe Fort Inhibitors of the ROCK Serine/Threonine Kinases: Key Effectors of the RhoA Small GTPase Dominico Vigil and Channing J. Der A Two-Hybrid Approach to Identify Inhibitors of the RAS-RAF Interaction Vladimir Khazak, Susanne Eyrisch, Juran Kato, Fuyuhiko Tamanoi and Erica A. Golemis Inhibitors of K-Ras Plasma Membrane Localization Kwang-jin Cho, Dharini van der Hoeven and John F. Hancock Ras Chaperons: New Targets for Cancer and Immunotherapy Yoel Kloog, Galit Elad-Sfadia, Roni Haklai and Adam Mor

巻冊次

pt. B ISBN 9780124201460

内容説明

Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss inhibitors of the Ras superfamily G-proteins.

目次

Discovery of Small-Molecule Ras Inhibitors that Display Anti-Tumor Activity by Interfering with Ras*GTP-Effector InteractionFumi Shima, Yoko Yoshikawa, Shigeyuki Matsumoto and Tohru Kataoka An Orthosteric Inhibitor of the RAS-SOS InteractionSeth Nickerson, Stephen T. Joy, Paramjit S. Arora and Dafna Bar-Sagi Conformation-Specific Inhibitors of Raf kinasesXiaolun Wang and Kristin Schleicher Inhibitors of the ERK Mitogen-activated Protein Kinase Cascade for Targeting RAS Mutant CancersLeanna Gentry, Ahmed A. Samatar and Channing J. Der Inhibiting the RAS - PI3K Pathway in Cancer TherapyClare Sheridan and Julian Downward The RalGEF/Ral Pathway: Evaluating an Intervention Opportunity for Ras CancersJonathan M. Cooper, Brian O. Bodemann and Michael A. White p21-Activated Kinase InhibitorsJoachim Rudolph, James J. Crawford, Klaus P. Hoeflich, and Jonathan Chernoff Recent Progress in Developing Small Molecule Inhibitors Designed to Interfere with Ras Membrane Association: Towards Inhibiting K-Ras and N-Ras Functions Fuyuhiko Tamanoi and Jie Lu Synthetic Lethal Genetic Screens in Ras Mutant CancersBing Yu and Ji Luo

「Nielsen BookData」 より

詳細情報

• NII書誌ID(NCID): BB13398807
• ISBN:
  • 9780124167490
  • 9780124201460
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam
• ページ数/冊数: v.
• 大きさ: 24 cm
• 分類:
  • DC23 : 572.6
• 件名:
  • LCSH : G proteins
• 親書誌ID:
  • BA00354062