Thymic development and selection of T lymphocytes

著者

書誌事項

Thymic development and selection of T lymphocytes

Thomas Boehm, Yousuke Takahama, editors

(Current topics in microbiology and immunology, 373)

Springer, c2014

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

目次

Development and Function of Cortical Thymic Epithelial Cells Kensuke Takada, Izumi Ohigashi, Michiyuki Kasai, Hiroshi Nakase, Yousuke Takahama Mechanisms of Thymus Medulla Development and Function Graham Anderson, Song Baik, Jennifer E. Cowan, Nicholas I. McCarthy, Kyoko Nakamura, Sonia M. Parnell, Andrea J. White, Peter J. L. Lane, Eric J. Jenkinson and William E. Jenkinson Self-Peptides in TCR Repertoire Selection and Peripheral T Cell Function Wan-Lin Lo and Paul M. Allen Central Tolerance Induction Maria L. Mouchess and Mark Anderson Trafficking to the Thymus Shirley Zhang and Avinash Bhandoola The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes Hirokazu Tanaka and Ichiro Taniuchi

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  • Current topics in microbiology and immunology

    Springer-Verlag 1967-

    41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 56 , 57 : gw , 57 : us , 58 , 59 : gw , 59 : us , 60 : gw , 60 : us , 61 : gw , 61 : us , 62 : gw , 62 : us , 63 : gw , 63 : us , 64 , 65 , 66 , 67 , v. 68 , v. 69 , v. 70 , v. 71 , v. 72 , v. 73 , v. 74 , v. 75 , v. 76 , v. 77 , v. 78 , v. 79 , v. 80 : gw , v. 80 : us , v. 82 , v. 83 , v. 84 : gw , v. 84 : us , v. 85 , v. 86 , v. 87 , v. 88 , v. 90 : gw , v. 90 : us , v. 91 : gw , v. 91 : us , v. 94-95 : gw , v. 94-95 : us , v. 97 : gw , v. 97 : us , v. 99 , v. 102 , v. 105 : gw , v. 114 : gw , v. 128 : gw , v. 128 : us , v. 129 : gw , v. 129 : us

    所蔵館22館

詳細情報

  • NII書誌ID(NCID)
    BB14105959
  • ISBN
    • 9783642402517
  • 出版国コード
    gw
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    Heidelberg
  • ページ数/冊数
    vii, 132 p.
  • 大きさ
    25 cm
  • 親書誌ID
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