Microbial synthetic biology
著者
書誌事項
Microbial synthetic biology
（Methods in microbiology / edited by J.R. Norris, D.W. Ribbons, v. 40）
Academic Press, 2013
- : hbk
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue.
目次
1. Computational Intelligence in the Design of Synthetic Microbial Genetic SystemsJennifer S. Hallinan2. Constraints in the Design of the Synthetic Bacterial ChassisAntoine Danchin and Agnieszka Sekowska3. Social Dimensions of Microbial Synthetic BiologyJane Calvert and Emma Frow4. Bacillus Subtilis: Model Gram-positive Synthetic Biology ChassisColin R. Harwood, Suzanne Pohl, Wendy Smith and Anil Wipat5. Engineering Microbial BiosensorsLisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont and Karen Polizzi6. Noise and Stochasticity in Gene Expression - A Pathogenic Fate determinantMikkel Girke Jorgensen, Renske van Raaphorst and Jan-Willem Veening7. Platforms for Genetic Design AutomationChris J. Myers
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