Stem cells and cartilage tissue engineering approaches to orthopaedic surgery

著者

    • Khan, Wasim S.
    • Hardingham, Timothy E.

書誌事項

Stem cells and cartilage tissue engineering approaches to orthopaedic surgery

Wasim S. Khan, Timothy E. Hardingham

(Surgery-procedures, complications, and results)

Nova Science Publishers, c2010

  • : softcover

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Tissue is frequently damaged or lost in injury and disease. There has been an increasing interest in stem cell applications and tissue engineering approaches in surgical practice to deal with damaged or lost tissue. Tissue engineering is an exciting strategy being explored to deal with damaged or lost tissue. It is the science of generating tissue using molecular and cellular techniques, combined with material engineering principles, to replace tissue. This could be in the form of cells with or without matrices. Although there have been developments in almost all surgical disciplines, the greatest advances are being made in orthopaedics, especially in cartilage repair. This is due to many factors including the familiarity with bone marrow derived mesenchymal stem cells and cartilage being a relatively simpler tissue to engineer. Unfortunately significant hurdles remain to be overcome in many areas before tissue engineering becomes more routinely used in clinical practice.

目次

  • Abstract
  • Stem Cells
  • Sources of Adult Mesenchymal Stem Cells
  • Differentiation of Stem Cells
  • Stem Cell Markers
  • Articular Cartilage
  • Current Surgical Treatment Modalities
  • Tissue Engineering Approaches for Articular Cartilage Defects
  • Conclusion
  • References
  • Index.

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