Statins : indications and uses, safety and modes of action

著者

    • Holmqvist, Gunnar N.

書誌事項

Statins : indications and uses, safety and modes of action

Gunnar N. Holmqvist, editor

（Nova biomedical）

Nova Science Publishers, c2009

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book focuses on statins which are a relatively new group of drugs used to lower blood cholesterol levels. A high cholesterol level increases a person's risk of having a heart attack or stroke. The long-term use of statins reduces the risk of such an event and can increase the life expectancy of people with a history of heart disease. The statins work by blocking an enzyme in the body that is involved in the production of LDL cholesterol, especially in the liver. This enzyme is known as HMG coenzyme A reductase. The statins are the most effective group of drugs for lowering the levels of LDL cholesterol in the body. Potential side-effects include muscle cramps and gastrointestinal upsets. These are usually resolved on temporarily lowering the dose. Liver enzyme derangements may occur, which generally return to normal after briefly discontinuing the drug. Some report headaches. Other side-effects occur rarely.

目次

  • Preface
  • Statin Therapy for Coronary Artery Disease Beyond Lipid Lowering Effect
  • Side Effects of Statins In Monotherapy
  • Preliminary findings about the trends of the renal hemodynamics and the proxies of cardiovascular risk during a short course of atorvastatin therapy in essential hypertensives
  • Beneficial effects of addition of fenofibrate to statin therapy in patients with acute coronary syndrome after percutaneous coronary interventions
  • Non-lipid lowering effects of statins
  • Statins in the Therapy of Acute Coronary Syndrome
  • Beneficial Effects of Addition of Fenofibrate to Statin Therapy in Patients with Acute Coronary Syndrome after Percutaneous Coronary Interventions
  • Bad HDL-C Responders to Statins
  • Beneficial Effects of Addition of Fenofibrate to Statin Therapy in Patients with Acute Coronary Syndrome after Percutaneous Coronary Interventions
  • Beneficial Effects of Statins in Systemic Lupus Erythematosus: Molecular Mechanism Involved
  • Index.

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