The molecular basis of cancer

著者

書誌事項

The molecular basis of cancer

John Mendelsohn ... [et al.]

Elsevier/Saunders, c2015

Ed. 4

大学図書館所蔵 件 / 全15件

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注記

Other editors: Joe W. Gray, Peter M. Howley, Mark A. Israel, Craig B. Thompson

Includes bibliographical references and index

内容説明・目次

内容説明

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.

目次

The Molecular Basis of Cancer, 4e Mendelsohn, Howley, Israel, Gray, Thompson Part I: Carcinogenesis and Cancer Genetics 1. Cancer, A Genetic Disorder 2. Oncogenes and Signal Transduction 3. Tumor Suppressor Genes 4. Genomic Instability and DNA Repair 5. Epigenetics and Cancer 6. Infectious Agents and Cancer 7. Environmental Carcinogenesis 8. Animal Models: Flies, Fish and Yeast 9. Genetic Mouse Models of Cancer Part II: Cancer Biology 10. Cancer Stem Cells 11. Regulation of the Cell Cycle 12. Cell Growth 13. Cancer Cell Metabolism 14. Apoptosis, Autophagy and Necrosis 15. Cell Growth Arrest and Senescence 16. Stromal-Cancer Interactions in the Microenvironment 17. Hypoxia and Angiogenesis 18. Invasion and Metastasis 19. Inflammation and Cancer 20. Molecular Pathways and Systems Biology Part III: Molecular Pathology and Diagnostics 21. Biomarkers Assessing Risk of Cancer 22. Biomarkers for Detecting Cancer: Molecular Screening 23. Biomarkers for Predicting Response to Specific Therapy 24. The Technology of Analyzing Nucleic Acids 25. Imaging Cancer

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