Introduction to evolutionary genomics
著者
書誌事項
Introduction to evolutionary genomics
(Computational biology, 17)
Springer, c2013
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.
目次
Part I: Basic Processes of Genome Evolution
Basic Metabolism Surrounding DNAs
Mutation
Phylogeny
Neutral Evolution
Natural Selection
Part II: Evolving Genomes
Brief History of Life
Prokaryote Genomes
Eukaryote Genomes
Vertebrate Genomes
Human Genomes
Part III: Methods for Evolutionary Genomics
Genome Sequencing
Omic Data Collection
Databases
Sequence Homology Handling
Evolutionary Distances
Tree and Network Building
Population Genomics
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