The multiple therapeutic targets of A20

著者
    • Ferran, Christiane
書誌事項

The multiple therapeutic targets of A20

edited by Christiane Ferran

(Advances in experimental medicine and biology, v. 809)

Springer Science+Business Media , Landes Bioscience, c2014

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target.

目次

A20-A Bipartite Ubiquitin Editing Enzyme with Immunoregulatory Potential.- The Biology of A20-Binding Inhibitors of NF- B Activation (Abins).- The Biology of A20-Like Molecules.- Anti-Viral Tetris: Modulation of the Innate Anti-Viral Immune Response by A20.- A20 Expressing Tumors and Anticancer Drug Resistance.- Translational Studies of A20 in Atherosclerosis and Cardiovascular Disease.- A Biomarker of Allograft Outcome: A Showcase in Kidney Transplantation.- A20-An Omnipotent Protein in the Liver: Prometheus Myth Resolved?.- Emerging Roles for A20 in Islet Biology and Pathology.- Single Nucleotide Polymorphisms at the TNFAIP3/A20 Locus and Susceptibility/Resistance to Inflammatory and Autoimmune Diseases.

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詳細情報
  • NII書誌ID(NCID)
    BB15398910
  • ISBN
    • 9781493903979
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    New York,Austin, Tex.
  • ページ数/冊数
    xxi, 188 p.
  • 大きさ
    27 cm
  • 件名
  • 親書誌ID
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