Mammalian transient receptor potential (TRP) cation channels
著者
書誌事項
Mammalian transient receptor potential (TRP) cation channels
（Handbook of experimental pharmacology, 222-223）
Springer, 2014
- v. 1 : hardcover
- v. 2 : hardcover
- v. 1 : softcover
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注記
Includes bibliographical references and index
Vol.1: xii, 726 p. ; v. 2: xi, p. [727]-1290
"Softcover reprint of the hardcover 1st edition 2014, c2014"--T.p. verso (v. 1 : softcover)
内容説明・目次
- 巻冊次
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v. 2 : hardcover ISBN 9783319051604
内容説明
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
目次
TRPs as Special Cell Sensors: Temperature Sensing with TRPs.- TRPs in Mechano-sensing and Volume Regulation.- TRPs as Chemosensors (ROS, RNS, RCS, Gasotransmitters).- Photosensitive TRPs.- TRPs in Taste and Chemesthesis.- Pain.- TRPs in Hearing.- TRPs in Olfaction.- TRP Structure.- Pain.- TRPs in Hearing.- TRP in Olfaction.- General Topics: Evolutionary Conserved, Multitasking TRP Channels-lessons From Worms and Flies.- TRPs as Novel Drug Targets.- TRPs in Endocrinology.- TRPs Modulation by Toxins.- TRPs and Phosphoinositides.- TRPs Modulation by Natural Compounds.- What do we Really Know and What do we Need to Know: Controversies, Perspectives, Surprises.
- 巻冊次
-
v. 1 : hardcover ISBN 9783642542145
内容説明
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
目次
TRPs -Truly Remarkable Proteins.- The TRCP Subfamily: TRPC1.- TRPC2.- TRPC3- a Multifunctional Signaling Molecule.- TRPC4 and TRPC4-Containing Channels.- TRPC5.- TRPC6: Physiological Function and Pathophysiological Relevance.- Transient Receptor Potential Canonical 7 (TRPC7).- The TRPV Subfamily: TRPV1.- TRPV2.- TRPV3.- The TRPV4 Channel.- TRPV5, a Ca2+ Channel for the Fine Tuning of Ca2+ Reabsorption.- TRPV6 Channels.- The TRPM Subfamily: TRPM1.- TRPM2.- TRPM3.-TRPM4.- TRPM5.- TRPM6.- TRPM7.- TRPM8.- The TRPA1, TRPML and TRPP Subfamily: TRPA1.- TRPML1: An Ion Channel in the Lysosome.- TRPML2 and Mucolipin Evolution.- TRPML3.- TRPP Subfamily and Polycystin-1 Proteins.
- 巻冊次
-
v. 1 : softcover ISBN 9783662512234
内容説明
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
目次
TRPs -Truly Remarkable Proteins.- The TRCP Subfamily: TRPC1.- TRPC2.- TRPC3- a Multifunctional Signaling Molecule.- TRPC4 and TRPC4-Containing Channels.- TRPC5.- TRPC6: Physiological Function and Pathophysiological Relevance.- Transient Receptor Potential Canonical 7 (TRPC7).- The TRPV Subfamily: TRPV1.- TRPV2.- TRPV3.- The TRPV4 Channel.- TRPV5, a Ca2+ Channel for the Fine Tuning of Ca2+ Reabsorption.- TRPV6 Channels.- The TRPM Subfamily: TRPM1.- TRPM2.- TRPM3.-TRPM4.- TRPM5.- TRPM6.- TRPM7.- TRPM8.- The TRPA1, TRPML and TRPP Subfamily: TRPA1.- TRPML1: An Ion Channel in the Lysosome.- TRPML2 and Mucolipin Evolution.- TRPML3.- TRPP Subfamily and Polycystin-1 Proteins.
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