Aminoacyl-tRNA synthetases in biology and medicine
著者
書誌事項
Aminoacyl-tRNA synthetases in biology and medicine
（Topics in current chemistry = Fortschritte der chemischen Forschung, 344）
Springer, c2014
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注記
Includes bibliographical references
内容説明・目次
内容説明
This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
目次
Catalysis.- Emergence and Evolution.- Architecture.- Protein-protein Interactions and Multicomponent Complexes.- Interactions with RNAs.- Secretion and Circulation.- Regulatory Roles.- Neural Diseases.- Cancer.- Immune Diseases.- Pathologic Implications of Mitochondrial tRNA Synthetases .- Infectious Diseases.- Reprogramming of Genetic Code.- Novel functions of tRNAs.- Perspectives for Systems and Synthetic Bio-Medicine.
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