Current advances in osteosarcoma

著者

• Kleinerman, Eugenie

書誌事項

Current advances in osteosarcoma

Eugenie S. Kleinerman, editor

（Advances in experimental medicine and biology, v. 804）

Springer, c2014

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Current Advances in Osteosarcoma edited by Dr. Eugenie S. Kleinerman summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer. It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. To improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. Current Advances in Osteosarcoma summarizes all of these new discoveries in one singular text, which will help move the field forward.

目次

Historical Perspective on the Introduction and Use of Chemotherapy for the Treatment of Osteosarcoma Norman Jaffe Wnt Signaling in Osteosarcoma Carol H Lin, Tao Ji, Cheng-Fong Chen, Bang H Hoang Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspects Ashley N. Rettew, Patrick J Getty, and Edward M. Greenberg Understanding the Role of Notch in Osteosarcoma Madonna M McManus, Kurt R Weiss, and Dennis PM Hughes Developmental Pathways Highjacked by Osteosarcoma Yi Zhang, Jared R Mortus, and Dennis PM Hughes MicroRNAs in Osteosarcomagenesis Lisa A Kafchinski and Kevin B Jones RECQ DNA Helicases and Osteosarcoma Linchao Lu, Weidong Jin, Hao Liu, and Lisa L Wang Autophagy in Osteosarcoma Janice Santiago O'Farrill and Nancy Gordon HER-2 Involvement in Osteosarcoma Jonathan Gill, David Geller, and Richard Gorlick Role of Ezrin in Osteosarcoma Metastasis Ling Ren and Chand Khanna Participation of the Fas/FasL Signaling Pathway and the Lung Microenvironment in the Development of Osteosarcoma Lung Metastases Gangxiong Huang, Kazumasa Nishimoto, Yuanzheng Yang, and Eugenie S Kleinerman Zebrafish as a Model for Human Osteosarcoma AB Mohseny and Pancras CW Hogendoorn Using Canine Osteosarcoma as a Model to Assess Efficacy of Novel Therapies: Can Old Dogs Teach Us New Tricks? Carlos O Rodriguez Oncolytic Viruses for Potential Osteosarcoma Therapy Pooja Hingorani, Valerie Sampson, Christina Lettieri, E. Anders Kolb IL-11R : A Novel Target for the Treatment of Osteosarcoma Valerae Lewis Bone-seeking Radiopharmaceuticals as Targeted Agents of Osteosarcoma: Samarium-153-EDTMP and Radium-223 Peter M Anderson, Vivek Subbiah, and Eric Rohren Muramyl Tripeptide-phophatidyl Ethanolamine Encapsulated in Lipomes (L-MTP-PE) in the Treatment of Osteosarcoma Paul A Meyers Genetically Modified T-cell Therapy for Osteosarcoma Christopher DeRenzo and Stephen Gottschalk Natural Killer Cells for Osteosarcoma Nidale Tarek, and Dean A Lee.

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詳細情報

• NII書誌ID(NCID): BB16051996
• ISBN:
  • 9783319048420
• LCCN: 2014938103
• 出版国コード: sz
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Cham
• ページ数/冊数: xii, 359 p.
• 大きさ: 25 cm
• 分類:
  • DC23 : 616.99471
• 件名:
  • LCSH : Osteosarcoma
• 親書誌ID:
  • BA00008720