Regulated cell death
著者
書誌事項
Regulated cell death
（Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan, v. 544-545）
Elsevier/Academic Press, c2014
- pt. A
- pt. B
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注記
Includes bibliographical references and indexes
収録内容
- Part A: Apoptotic mechanisms
- Part:B: Necroptotic, autophagic and other non-apoptotic mechanisms
内容説明・目次
- 巻冊次
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pt. A ISBN 9780124171589
内容説明
Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.
目次
1. Examining the Molecular Mechanism of Bcl-2 Family Proteins at Membranes by Fluorescence Spectroscopy.
2. Photoreactive Stapled Peptides to Identify and Characterize BCL-2 Family Interaction Sites by Mass Spectrometry
3. The Structural Biology of BH3-only proteins
4. How to Analyze Mitochondrial Morphology in Healthy Cells and Apoptotic Cells in Caenorhabditis elegans
5. Apoptosis Initiation Through the Cell-Extrinsic Pathway
6. Using RNAi Screening Technologies to Interrogate the Extrinsic Apoptosis Pathway
7. Caspase Enzymology and Activation Mechanisms
8. Turning ON Caspases with Genetics and Small Molecules
9. A Multi-Pronged Approach for Compiling a Global Map of Allosteric Regulation in the Apoptotic Caspases
10. Measuring Caspase Activity in vivo
11. Single-Molecule Sensing of Caspase Activation in Live Cells via Plasmon Coupling Nanotechnology
12. In vivo Monitoring of Caspase Activation Using a Fluorescence Resonance Energy Transfer-Based Tfluorescent Probe
13. Global Analysis of Cellular Proteolysis by Selective Enzymatic Labeling of Protein N-termini
14. Complementary Methods for the Identification of Substrates of Proteolysis
15. Phospholipid Scrambling on the Plasma Membrane
16. Studying Apoptosis in the Zebrafish
- 巻冊次
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pt. B ISBN 9780128014301
内容説明
Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.
目次
1. Assays for Necroptosis and Activity of RIP Kinases
2. IAP Family of Cell Death and Signaling Regulators
3. Activation of the NLRP3 Inflammasome by Proteins that Signal for Necroptosis
4. Characterization of the Ripoptosome and its Components - Implications for Anti-Inflammatory and Cancer Therapy
5. Tools and Techniques to Study Ligand-Receptor Interactions and Receptor Activation by TNF Superfamily Members
6. Necrotic Cell Death in Caenorhabditis elegans
7. Noncanonical Cell Death in the Nematode Caenorhabditis elegans
8. Autophagy and Cell Death in the Fly
9. Structural Studies of Death Receptors
10. Use of E2~Ubiquitin Conjugates for the Characterization of Ubiquitin Transfer by RING E3 Ligases such as the Inhibitor of Apoptosis Proteins
11. Multidimensional Profiling in the Investigation of Small-Molecule-Induced Cell Death
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