Mechanotransduction

著者

• Engler, Adam J.
• Kumar, Sanjay

書誌事項

Mechanotransduction

edited by Adam J. Engler, Sanjay Kumar

（Progress in molecular biology and translational science, v. 126）

Elsevier/Academic Press, 2014

内容説明・目次

内容説明

Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references. Volume 126 features in-depth reviews that focus on the tools required to investigate mechanotransduction. Additional chapters focus on how we can use these tools to answer fundamental questions about the interaction of physical forces with cell biology, morphogenesis, and function of mature structures. Chapters in the volume are authored by a unique combination of cell biologists and engineers, providing a range of perspectives on mechanotransduction.

目次

Subcellular tools for activating and measuring mechanotransductive signaling 1. The Detection and Role of Molecular Tension in Focal Adhesion DynamicsBrenton D. Hoffman2. Single Cell Imaging of Mechanotransduction in Endothelial CellsShaoying Lu and Yingxiao Wang Focal adhesions as sensors 3. Focal Adhesions as SensorsJean-Cheng Kuo4. Focal Adhesions as SensorsWolfgang H. Goldmann5. Mechanical Cues Direct Focal Adhesion DynamicsKristina Haase, Zeinab Al-Rekabi and Andrew E. Pelling6. Molecular Mechanisms Underlying the Force-Dependent Regulation of Actin-to-ECM Linkage at the Focal AdhesionsHiroaki Hirata, Masahiro Sokabe and Chwee Teck Lim Nuclear Mechanisms of Sensing 7. The Cellular Mastermind(?) - Mechanotransduction and the NucleusAshley Kaminski, Gregory R. Fedorchak and Jan Lammerding8. Nuclear Forces and Cell Mechano-SensingSamer Alam, David B. Lovett, Richard B. Dickinson, Kyle J. Roux and Tanmay P. Lele Mechano-sensing in Stem Cells 9. From Stem Cells to Cardiomyocytes: The Role of Forces in Cardiac Maturation, Aging, and DiseaseGaurav Kaushik and Adam J. Engler10. Matrix Regulation of Tumor-Initiating CellsSophie Y. Wong and Sanjay Kumar11. Biomaterials Approaches in Stem Cell MechanobiologyNikolche Gjorevski and Matthias Lutolf Multi-cellular Sensing 12. Mechanotransduction in C. elegans Morphogenesis and Tissue FunctionErin J. Cram13. Mechanical Force Sensing in TissuesSoline Chanet and Adam C. Martin

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詳細情報

• NII書誌ID(NCID): BB16460838
• ISBN:
  • 9780123946249
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam
• ページ数/冊数: xiv, 365 p., [24] p. of plates
• 大きさ: 23 cm
• 親書誌ID:
  • BA88526923