Glycans in diseases and therapeutics
Author(s)
Bibliographic Information
Glycans in diseases and therapeutics
（Biology of extracellular matrix）
Springer, c2011
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Includes bibliographical references and index
Description and Table of Contents
Description
Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.
This volume of the series "Biology of Extracellular Matrix" reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.
Table of Contents
Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis.- Heparan Sulfate Proteoglycans in Infection.- Glycans in cancer.- Glycosaminoglycans in atherosclerosis and thrombosis.- Glycans in Embryonic Stem Cells.- Heparan sulfate proteoglycans in cancer progression and therapy.- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.
by "Nielsen BookData"
