Transcriptional control of lineage differentiation in immune cells
著者
書誌事項
Transcriptional control of lineage differentiation in immune cells
（Current topics in microbiology and immunology, 381）
Springer, c2014
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during the differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.
目次
Genetic and epigenetic control of early lymphocyte development
Tomokatsu Ikawa
The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity
Wilfried Ellmeier and Ichiro Taniuchi
Transcriptional control of the development and function of V 14i NKT cells
Isaac Engel and Mitchell Kronenberg
Transcriptional Control of Regulatory T cells
Michael Delacher, Lisa Schreiber, David D. Richards, Carla Farah, Markus Feuerer, Jochen Huehn
Transcriptional regulatory networks for CD4 T cell differentiation
Darah Christie and Jinfang Zhu
Transcriptional control of NK cell differentiation and function
Victoria Male and Hugh J.M. Brady
Transcriptional control of pre-B cell development and leukemia prevention
Swee Heng Milon Pang, Sebastian Carotta and Stephen L Nutt
Transcription factors controlling innate lymphoid cell fate decisions
Christoph S.N. Klose and Andreas Diefenbach
Transcriptional control of dendritic cell differentiation
Izumi Sasaki, Tsuneyasu Kaisho
Helper T cell plasticity: Impact of Extrinsic and Intrinsic Signals On Transcriptomes and Epigenomes
Michael Bonelli, Han-Yu Shih, Kiyoshi Hirahara, Kentner Singelton, Arian Laurence, Amanda Poholek, Tim Hand, Yohei Mikami, Golnaz Vahedi, Yuka Kanno and John J. O'Shea
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