The mitochondrion in aging and disease
著者
書誌事項
The mitochondrion in aging and disease
（Progress in molecular biology and translational science, v. 127）
Elsevier/Academic Press, 2014
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Mitochondria, the "power plants" of eukaryotic cells, are best known for the generation of adenosine triphosphate (ATP), the universal cellular "energy currency" of the cell, and the synthesis of different essential components. Mitochondrial dysfunction is known to lead to various degenerative disorders, disease, and aging. The Mitochondrion in Aging and Disease works to unravel the processes leading to mitochondrial impairments and of pathways involved in mitochondrial quality control and their impact on health and aging will be addressed.
目次
The Mitochondrial Free Radical Theory of Aging
Gustavo Barja
Mitochondrial DNA Mutations in Aging
Konstantin Khrapko and Doug Turnbull
Mathematical Models of Mitochondrial Aging and Dynamics
Axel Kowald and Edda Klipp
Mitochondrial Dynamics in Aging and Disease
Jurgen Bereiter-Hahn
The Retrograde Response - A Conserved Compensatory Reaction to Damage from Within and from Without
S. Michal Jazwinski
Mitochondrial Acetylation and Genetic Models of Parkinson's Disease
Georg Auburger, Suzana Gispert and Marina Jendrach
Mitochondrial Dysfunction: Cause and Consequence of Alzheimer's Disease
Kristina Friedland-Leuner, Carola Stockburger, Isabel Denzer, Gunter P. Eckert and Walter E. Muller
Mitochondria in Cancer: Why Mitochondria are a Good Target for Cancer Therapy
Lan-Feng Dong and Jiri Neuzil
Estrogen and Mitochondria Function in Cardiorenal Metabolic Syndrome
Guanghong Jia, Annayya R. Aroor and James R. Sowers
Advances in Development of Rechargeable Mitochondrial Antioxidants
Alexander N. Lukashev, Maxim V. Skulachev, Victoria Ostapenko, Alla Yu. Savchenko, V. V. Pavshintsev and Vladimir P. Skulachev
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