The mitochondrion in aging and disease

Author(s)

• Osiewacz, Heinz D.

Bibliographic Information

The mitochondrion in aging and disease

edited by Heine D. Osiewacz

（Progress in molecular biology and translational science, v. 127）

Elsevier/Academic Press, 2014

Note

Includes bibliographical references and index

Description and Table of Contents

Description

Mitochondria, the "power plants" of eukaryotic cells, are best known for the generation of adenosine triphosphate (ATP), the universal cellular "energy currency" of the cell, and the synthesis of different essential components. Mitochondrial dysfunction is known to lead to various degenerative disorders, disease, and aging. The Mitochondrion in Aging and Disease works to unravel the processes leading to mitochondrial impairments and of pathways involved in mitochondrial quality control and their impact on health and aging will be addressed.

Table of Contents

The Mitochondrial Free Radical Theory of Aging Gustavo Barja Mitochondrial DNA Mutations in Aging Konstantin Khrapko and Doug Turnbull Mathematical Models of Mitochondrial Aging and Dynamics Axel Kowald and Edda Klipp Mitochondrial Dynamics in Aging and Disease Jurgen Bereiter-Hahn The Retrograde Response - A Conserved Compensatory Reaction to Damage from Within and from Without S. Michal Jazwinski Mitochondrial Acetylation and Genetic Models of Parkinson's Disease Georg Auburger, Suzana Gispert and Marina Jendrach Mitochondrial Dysfunction: Cause and Consequence of Alzheimer's Disease Kristina Friedland-Leuner, Carola Stockburger, Isabel Denzer, Gunter P. Eckert and Walter E. Muller Mitochondria in Cancer: Why Mitochondria are a Good Target for Cancer Therapy Lan-Feng Dong and Jiri Neuzil Estrogen and Mitochondria Function in Cardiorenal Metabolic Syndrome Guanghong Jia, Annayya R. Aroor and James R. Sowers Advances in Development of Rechargeable Mitochondrial Antioxidants Alexander N. Lukashev, Maxim V. Skulachev, Victoria Ostapenko, Alla Yu. Savchenko, V. V. Pavshintsev and Vladimir P. Skulachev

by "Nielsen BookData"

Details

• NCID: BB16776900
• ISBN:
  • 9780123946256
• Country Code: ne
• Title Language Code: eng
• Text Language Code: eng
• Place of Publication: Amsterdam
• Pages/Volumes: xiii, 275 p., [10] p. of plates
• Size: 24 cm
• Classification:
  • DC23 : 616.07
• Subject Headings:
  • LCSH : Mitochondrial pathology
  • LCSH : Mitochondria
  • LCSH : Aging
• Parent Bibliography ID:
  • BA88526923