Microbicides for prevention of HIV infection
著者
書誌事項
Microbicides for prevention of HIV infection
（Current topics in microbiology and immunology, 383）
Springer, c2014
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
目次
Candidate Microbicides and Their Mechanisms of Action
Carolina Herrera and Robin J. Shattock
Microbicide Dosage Forms
L.C. Rohan, B. Devlin and H. Yang
Preclinical Safety Evaluation
Jonathon D. S. Holt and Jeremy P. Nuttall
Clinical Safety and Pharmacology Trial
Christine Mauck, Andrea Thurman and Jill Schwartz
Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials
Salim S. Abdool Karim and Cheryl Baxter
Rectal Microbicide Development
Ian McGowan and Charlene Dezzutti
Developing Regulatory Strategy for Microbicides
Ronald Nardi, Linda Arterburn, and Lisa Carlton
Preparing for Microbicide Introduction, Rollout and Sustained Access
Cynthia Woodsong, Tim Farley and Elizabeth McGrory
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