Microbicides for prevention of HIV infection

Author(s)

    • Nuttall, Jeremy

Bibliographic Information

Microbicides for prevention of HIV infection

Jeremy Nuttall, editor

(Current topics in microbiology and immunology, 383)

Springer, c2014

Available at  / 6 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.

Table of Contents

Candidate Microbicides and Their Mechanisms of Action Carolina Herrera and Robin J. Shattock Microbicide Dosage Forms L.C. Rohan, B. Devlin and H. Yang Preclinical Safety Evaluation Jonathon D. S. Holt and Jeremy P. Nuttall Clinical Safety and Pharmacology Trial Christine Mauck, Andrea Thurman and Jill Schwartz Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials Salim S. Abdool Karim and Cheryl Baxter Rectal Microbicide Development Ian McGowan and Charlene Dezzutti Developing Regulatory Strategy for Microbicides Ronald Nardi, Linda Arterburn, and Lisa Carlton Preparing for Microbicide Introduction, Rollout and Sustained Access Cynthia Woodsong, Tim Farley and Elizabeth McGrory

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