CiNii 図書 - Commercial plant-produced recombinant protein products : case studies

Attention has recently turned to using plants as hosts for the production of commercially important proteins. The twelve case studies in this volume present successful strategies for using plants to produce industrial and pharmaceutical proteins and vaccine antigens. They examine in detail projects that have commercial potential or products that have already been commercialized, illustrating the advantages that plants offer over bacterial, fungal or animal cell-culture hosts. There are many indications that plant protein production marks the beginning of a new paradigm for the commercial production of proteins that, over the next decade, will expand dramatically.

1 Introduction - Plant-produced protein products Elizabeth E. Hood and Paul Christou Part I: Highly Purified Proteins 2 Commercial Plant-Produced Recombinant Avidin Elizabeth E. Hood and John A. Howard 3 Molecular farming in plants - the long road to the market Rainer Fischer, Johannes F Buyel, Stefan Schillberg and Richard M Twyman 4 TrypZean (TM): an animal-free alternative to bovine trypsin Aparna Krishnan, Susan L. Woodard 5 Production of Pharmaceutical Grade Recombinant Native Aprotinin and Non-Oxidized Aprotinin-Variants Under Greenhouse and Field Conditions Gregory P. Pogue, Fakhrieh Vojdani, Kenneth E. Palmer, Earl White, Hugh Haydon, Barry Bratcher Part II: Vaccines 6 Influenza virus-like particles produced in Nicotiana benthamiana protect against a lethal viral challenge in mice Louis-P Vezina, Brian J Ward, Marc-Andre D'Aoust, Manon Couture, Sonia Trepanier, Andrew Sheldon1, Nathalie Landry 7 Plant-Produced Recombinant Transmission Blocking Vaccine Candidates to Combat Malaria Stephen J. Streatfield, Natasha Kushnir, Vidadi Yusibov 8 An oral vaccine for TGEV immunization of pigs Rajan, V. 9 Edible Rabies Vaccines Elizabeth Loza-Rubio and Edith Rojas-Anaya 10 Newcastle disease vaccines Miguel A. Gomez Lim 11 An oral vaccine for hepatitis B: challenges, setbacks, and breakthroughs Celine A. Hayden Part III: Industrial Proteins 12 Commercial Plant-Produced Recombinant Cellulases for Biomass Conversion Elizabeth E. Hood, Deborah V. Requesens 13 Brazzein: A High Intensity Natural Sweetener Gina Fake and John Howard Part IV: Future Directions 14 The Future of Plant-Produced Pharmaceuticals and Industrial Proteins John Howard, Elizabeth E. Hood

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Commercial plant-produced recombinant protein products : case studies

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